Multiple eruptive pilomatricomas in a 9-year-old boy with glioblastoma

S. Tyler Hollmig, Megha M. Tollefson, Jinah Kim, Phuong Khuu

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

A 9-year-old male presented to our dermatology clinic with a recent history of developing numerous cutaneous pilomatricomas, and was subsequently discovered to have sustained a recurrence of his glioblastoma multiforme. Immunohistochemical staining of a representative pilomatricoma and his original brain tumor revealed upregulation and nuclear localization of beta-catenin, a sign associated with poor prognosis in glioblastoma. We hypothesize that the development of multiple pilomatricomas may have been a hallmark of this patient's tumor recurrence and provide support for a recent report of an association between multiple pilomatricomas and gliomatosis cerebri.

Original languageEnglish (US)
Pages (from-to)756-758
Number of pages3
JournalPediatric Dermatology
Volume30
Issue number6
DOIs
StatePublished - Nov 1 2013

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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