Multiple eruptive pilomatricomas in a 9-year-old boy with glioblastoma

S. Tyler Hollmig, Megha M. Tollefson, Jinah Kim, Phuong Khuu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A 9-year-old male presented to our dermatology clinic with a recent history of developing numerous cutaneous pilomatricomas, and was subsequently discovered to have sustained a recurrence of his glioblastoma multiforme. Immunohistochemical staining of a representative pilomatricoma and his original brain tumor revealed upregulation and nuclear localization of beta-catenin, a sign associated with poor prognosis in glioblastoma. We hypothesize that the development of multiple pilomatricomas may have been a hallmark of this patient's tumor recurrence and provide support for a recent report of an association between multiple pilomatricomas and gliomatosis cerebri.

Original languageEnglish (US)
Pages (from-to)756-758
Number of pages3
JournalPediatric Dermatology
Volume30
Issue number6
DOIs
StatePublished - Nov 2013
Externally publishedYes

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Pilomatrixoma
Glioblastoma
Neuroepithelial Neoplasms
Recurrence
beta Catenin
Dermatology
Brain Neoplasms
Up-Regulation
Staining and Labeling
Skin
Neoplasms

ASJC Scopus subject areas

  • Dermatology
  • Pediatrics, Perinatology, and Child Health

Cite this

Multiple eruptive pilomatricomas in a 9-year-old boy with glioblastoma. / Hollmig, S. Tyler; Tollefson, Megha M.; Kim, Jinah; Khuu, Phuong.

In: Pediatric Dermatology, Vol. 30, No. 6, 11.2013, p. 756-758.

Research output: Contribution to journalArticle

Hollmig, S. Tyler ; Tollefson, Megha M. ; Kim, Jinah ; Khuu, Phuong. / Multiple eruptive pilomatricomas in a 9-year-old boy with glioblastoma. In: Pediatric Dermatology. 2013 ; Vol. 30, No. 6. pp. 756-758.
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