Abstract
A 9-year-old male presented to our dermatology clinic with a recent history of developing numerous cutaneous pilomatricomas, and was subsequently discovered to have sustained a recurrence of his glioblastoma multiforme. Immunohistochemical staining of a representative pilomatricoma and his original brain tumor revealed upregulation and nuclear localization of beta-catenin, a sign associated with poor prognosis in glioblastoma. We hypothesize that the development of multiple pilomatricomas may have been a hallmark of this patient's tumor recurrence and provide support for a recent report of an association between multiple pilomatricomas and gliomatosis cerebri.
Original language | English (US) |
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Pages (from-to) | 756-758 |
Number of pages | 3 |
Journal | Pediatric Dermatology |
Volume | 30 |
Issue number | 6 |
DOIs | |
State | Published - Nov 2013 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Dermatology