Multiple Cystic Fibrohistiocytic Tumors of the Lung: Report of Two Cases

MARIAMMA G. JOSEPH, THOMAS V. COLBY, STEPHEN J. SWENSEN, JAROSLAV P. MIKUS, EDWARD A. GAENSLER

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Abstract

We describe two adults with multiple cystic fibrohistiocytic tumors of the lung that manifested as bilateral nodular opacities, cystic lesions, or both on chest roentgenograms. One patient had recurrent episodes of pneumothorax and intermittent shortness of breath; the other was asymptomatic. Open-lung biopsy speeimens showed identical histologically benign fibrohistiocytic proliferations associated with formation of cysts that were lined by metaplastic bronchiolar, squamous, or type II alveolar epithelium and old hemorrhage in the cysts. In both patients, the lesions grew slowly over a period of years. These unusual multiple bilateral fibrohistiocytic tumors of the lung should be included in the differential diagnosis of bilateral cystic lesions in the lung.

Original languageEnglish (US)
Pages (from-to)192-197
Number of pages6
JournalMayo Clinic proceedings
Volume65
Issue number2
DOIs
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Medicine(all)

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    JOSEPH, MARIAMMA. G., COLBY, THOMAS. V., SWENSEN, STEPHEN. J., MIKUS, JAROSLAV. P., & GAENSLER, EDWARD. A. (1990). Multiple Cystic Fibrohistiocytic Tumors of the Lung: Report of Two Cases. Mayo Clinic proceedings, 65(2), 192-197. https://doi.org/10.1016/S0025-6196(12)65014-9