Multifunctional system for observing, measuring and analyzing stimulation-evoked neurochemical signaling

Christopher J. Kimble, Joshua B. Boesche, Diane R. Eaker, Kenneth R. Kressin, Malcolm B. McIntosh, Jose Lujan, James K. Trevathan, Seungleal Paek, Anders J. Asp

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The ability to measure neurotransmitter activity using implanted electrochemical sensors offers researchers a potent technique for analyzing neural activity across specific neural circuitry. We have developed a wirelessly controlled device, WINCS Harmoni, to observe and measure neurotransmitter dynamics at up to four separate sensors, with high temporal and spatial resolution. WINCS Harmoni also incorporates a versatile neurostimulator that can be synchronized with electrochemical recording. The WINCS Harmoni platform is thus optimally suited for probing the neurochemical effects of neurostimulation, and may in turn enable the development of personalized therapies for multiple brain disorders.

Original languageEnglish (US)
Title of host publication2017 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages349-354
Number of pages6
ISBN (Electronic)9781509029839
DOIs
StatePublished - Jul 19 2017
Event12th IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017 - Rochester, United States
Duration: May 7 2017May 10 2017

Other

Other12th IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017
CountryUnited States
CityRochester
Period5/7/175/10/17

Keywords

  • neuro-modulation
  • neurotransmitter
  • stimulation
  • voltammetry

ASJC Scopus subject areas

  • Instrumentation
  • Computer Science Applications
  • Medicine (miscellaneous)

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    Kimble, C. J., Boesche, J. B., Eaker, D. R., Kressin, K. R., McIntosh, M. B., Lujan, J., Trevathan, J. K., Paek, S., & Asp, A. J. (2017). Multifunctional system for observing, measuring and analyzing stimulation-evoked neurochemical signaling. In 2017 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017 - Proceedings (pp. 349-354). [7985901] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MeMeA.2017.7985901