Multidimensional ultrasound imaging of the wrist: Changes of shape and displacement of the median nerve and tendons in carpal tunnel syndrome

Anika Filius, Marjan Scheltens, Hans G. Bosch, Pieter A. Van Doorn, Henk J. Stam, Steven E R Hovius, Peter C Amadio, Ruud W. Selles

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Dynamics of structures within the carpal tunnel may alter in carpal tunnel syndrome (CTS) due to fibrotic changes and increased carpal tunnel pressure. Ultrasound can visualize these potential changes, making ultrasound potentially an accurate diagnostic tool. To study this, we imaged the carpal tunnel of 113 patients and 42 controls. CTS severity was classified according to validated clinical and nerve conduction study (NCS) classifications. Transversal and longitudinal displacement and shape (changes) were calculated for the median nerve, tendons and surrounding tissue. To predict diagnostic value binary logistic regression modeling was applied. Reduced longitudinal nerve displacement (p≤0.019), increased nerve cross-sectional area (p≤0.006) and perimeter (p≤0.007), and a trend of relatively changed tendon displacements were seen in patients. Changes were more convincing when CTS was classified as more severe. Binary logistic modeling to diagnose CTS using ultrasound showed a sensitivity of 70-71% and specificity of 80-84%. In conclusion, CTS patients have altered dynamics of structures within the carpal tunnel.

Original languageEnglish (US)
Pages (from-to)1332-1340
Number of pages9
JournalJournal of Orthopaedic Research
Volume33
Issue number9
DOIs
StatePublished - Sep 1 2015

Fingerprint

Carpal Tunnel Syndrome
Median Nerve
Wrist
Tendons
Ultrasonography
Neural Conduction
Logistic Models
Pressure

Keywords

  • biomechanics
  • Carpal tunnel syndrome
  • displacement
  • tendon
  • ultrasound

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Filius, A., Scheltens, M., Bosch, H. G., Van Doorn, P. A., Stam, H. J., Hovius, S. E. R., ... Selles, R. W. (2015). Multidimensional ultrasound imaging of the wrist: Changes of shape and displacement of the median nerve and tendons in carpal tunnel syndrome. Journal of Orthopaedic Research, 33(9), 1332-1340. https://doi.org/10.1002/jor.22909

Multidimensional ultrasound imaging of the wrist : Changes of shape and displacement of the median nerve and tendons in carpal tunnel syndrome. / Filius, Anika; Scheltens, Marjan; Bosch, Hans G.; Van Doorn, Pieter A.; Stam, Henk J.; Hovius, Steven E R; Amadio, Peter C; Selles, Ruud W.

In: Journal of Orthopaedic Research, Vol. 33, No. 9, 01.09.2015, p. 1332-1340.

Research output: Contribution to journalArticle

Filius, Anika ; Scheltens, Marjan ; Bosch, Hans G. ; Van Doorn, Pieter A. ; Stam, Henk J. ; Hovius, Steven E R ; Amadio, Peter C ; Selles, Ruud W. / Multidimensional ultrasound imaging of the wrist : Changes of shape and displacement of the median nerve and tendons in carpal tunnel syndrome. In: Journal of Orthopaedic Research. 2015 ; Vol. 33, No. 9. pp. 1332-1340.
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