Abstract
We studied two cases of a recently recognized systemic lymphoproliferative disease with morphologic features of Castleman's disease: multicentric giant lymph node hyperplasia. Both patients developed Kaposi's sarcoma and had laboratory evidence of immune abnormalities, including reversed T4 to T8 ratios. One patient's disease had a subacute course with fevers of unknown origin, mucocutaneous candidiasis, and progressive thrombocytopenia, while the other patient's disease had a fulminant course with anemia, thrombocytopenia, and splenic lymphoma. Both patients were elderly, and both died of complications of multicentric giant lymph node hyperplasia.
Original language | English (US) |
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Pages (from-to) | 1013-1018 |
Number of pages | 6 |
Journal | Archives of Pathology and Laboratory Medicine |
Volume | 109 |
Issue number | 11 |
State | Published - 1985 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology