Multicenter Experience of Surgical Explantation of Carotid Stents for Recurrent Stenosis

Jesse A. Columbo, John C. McCallum, Philip P. Goodney, Thomas C. Bower, Marc L. Schermerhorn, Richard J. Powell, Randall R De Martino

Research output: Contribution to journalArticle

Abstract

Objective: A significant cohort of patients who have undergone carotid artery stenting (CAS) will have in-stent restenosis (ISR). The optimal management of symptomatic or severe ISR remains poorly defined. The purpose of this study was to describe the indications, treatment, and mid- to long-term outcomes of patients undergoing CAS explantation for ISR. Methods: All patients undergoing internal carotid artery stent explantation with carotid artery reconstruction at Mayo Clinic Rochester, Dartmouth-Hitchcock Medical Center, and Beth-Israel Deaconess Medical Center from 2003 to 2013 were retrospectively reviewed. Isolated common carotid artery stents were excluded. Demographics, comorbidities, indications for explantation, operative details, and perioperative and postoperative outcomes were reviewed. Results: Over the study interval, a total of 971 patients underwent carotid stenting across the 3 centers. Of these, 8 patients ultimately underwent CAS explantation with carotid artery reconstruction. Mean age was 69 years and 5 patients were male. Index stent placement was for symptomatic stenosis in 4 patients, asymptomatic restenosis after endarterectomy in 2 patients, asymptomatic high lesion in 1 patient, and asymptomatic critical stenosis in 1 patient. Indications for explantation were symptomatic ISR in 4 patients and asymptomatic severe ISR in 4 patients. Method of repair was stent explantation and patch angioplasty in 5 and en bloc carotid resection with bypass in 3 patients. There were no perioperative neurologic events or cranial nerve injuries. At a mean follow-up of 38.7 months, there were 2 late disabling ipsilateral strokes (14.4 months and 19.1 months). Conclusion: A significant cohort of patients who have undergone CAS will have ISR. Although excellent perioperative results after surgical explantation can be obtained, this patient subgroup remains at risk for late neurologic events. Appropriate patient selection and diligent long-term follow-up are mandated to obtain optimal outcomes.

Original languageEnglish (US)
Pages (from-to)547-553
Number of pages7
JournalVascular and Endovascular Surgery
Volume50
Issue number8
DOIs
StatePublished - 2016

Fingerprint

Stents
Pathologic Constriction
Carotid Arteries
Nervous System
Cranial Nerve Injuries
Endarterectomy
Common Carotid Artery
Internal Carotid Artery
Israel
Angioplasty
Patient Selection
Comorbidity
Stroke
Demography

Keywords

  • carotid stent explantation
  • carotid stent removal
  • carotid stent restenosis
  • carotid stenting

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

Cite this

Columbo, J. A., McCallum, J. C., Goodney, P. P., Bower, T. C., Schermerhorn, M. L., Powell, R. J., & De Martino, R. R. (2016). Multicenter Experience of Surgical Explantation of Carotid Stents for Recurrent Stenosis. Vascular and Endovascular Surgery, 50(8), 547-553. https://doi.org/10.1177/1538574416677668

Multicenter Experience of Surgical Explantation of Carotid Stents for Recurrent Stenosis. / Columbo, Jesse A.; McCallum, John C.; Goodney, Philip P.; Bower, Thomas C.; Schermerhorn, Marc L.; Powell, Richard J.; De Martino, Randall R.

In: Vascular and Endovascular Surgery, Vol. 50, No. 8, 2016, p. 547-553.

Research output: Contribution to journalArticle

Columbo, JA, McCallum, JC, Goodney, PP, Bower, TC, Schermerhorn, ML, Powell, RJ & De Martino, RR 2016, 'Multicenter Experience of Surgical Explantation of Carotid Stents for Recurrent Stenosis', Vascular and Endovascular Surgery, vol. 50, no. 8, pp. 547-553. https://doi.org/10.1177/1538574416677668
Columbo, Jesse A. ; McCallum, John C. ; Goodney, Philip P. ; Bower, Thomas C. ; Schermerhorn, Marc L. ; Powell, Richard J. ; De Martino, Randall R. / Multicenter Experience of Surgical Explantation of Carotid Stents for Recurrent Stenosis. In: Vascular and Endovascular Surgery. 2016 ; Vol. 50, No. 8. pp. 547-553.
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