TY - GEN
T1 - Multi-task learning with selective cross-task transfer for predicting bleeding and other important patient outcomes
AU - Ngufor, Che
AU - Upadhyaya, Sudhindra
AU - Murphree, Dennis
AU - Kor, Daryl
AU - Pathak, Jyotishman
N1 - Publisher Copyright:
© 2015 IEEE.
PY - 2015/12/2
Y1 - 2015/12/2
N2 - In blood transfusion studies, its is often desirable before a surgical procedure to estimate the likelihood of a patient bleeding, need for blood products, re-operation due to bleeding and other important patient outcomes. Such prediction rules are crucial in allowing for optimal planning, more efficient use of blood bank resources, and identification of high-risk patient cohort for specific perioperative interventions. The goal of this study is to present a simple and efficient algorithm that could estimate the risk of multiple outcomes simultaneously. Specifically, a heterogeneous multi-task learning method is presented for learning important surgical outcomes such as bleeding, intraoperative RBC transfusion, need for ICU care, length of stay and mortality. To improve the performance of the method, a post-learning strategy is implemented to further learn the relationship between the trained tasks by a simple goodness of fit measure. Specifically, two tasks are considered similar if the model parameters of one tasks improves predictive performance of the other. This strategy allows tasks to be grouped in clusters where selective cross-task transfer of knowledge is explicitly encouraged. To further improve prediction accuracy, a number of operative measurements or surgical outcomes whose predictions are not of direct interest are incorporated in the multi-task model as supplementary tasks to donate information and help the performance of relevant tasks. Results for predicting bleeding and need for blood transfusion for patients undergoing non-cardiac operations from an institutional transfusion datamart show that the proposed methods can improve prediction accuracy over standard single-tasks learning methods. Additional experiments on a real public available data set show that the method is accurate and competitive with some existing methods in the literature.
AB - In blood transfusion studies, its is often desirable before a surgical procedure to estimate the likelihood of a patient bleeding, need for blood products, re-operation due to bleeding and other important patient outcomes. Such prediction rules are crucial in allowing for optimal planning, more efficient use of blood bank resources, and identification of high-risk patient cohort for specific perioperative interventions. The goal of this study is to present a simple and efficient algorithm that could estimate the risk of multiple outcomes simultaneously. Specifically, a heterogeneous multi-task learning method is presented for learning important surgical outcomes such as bleeding, intraoperative RBC transfusion, need for ICU care, length of stay and mortality. To improve the performance of the method, a post-learning strategy is implemented to further learn the relationship between the trained tasks by a simple goodness of fit measure. Specifically, two tasks are considered similar if the model parameters of one tasks improves predictive performance of the other. This strategy allows tasks to be grouped in clusters where selective cross-task transfer of knowledge is explicitly encouraged. To further improve prediction accuracy, a number of operative measurements or surgical outcomes whose predictions are not of direct interest are incorporated in the multi-task model as supplementary tasks to donate information and help the performance of relevant tasks. Results for predicting bleeding and need for blood transfusion for patients undergoing non-cardiac operations from an institutional transfusion datamart show that the proposed methods can improve prediction accuracy over standard single-tasks learning methods. Additional experiments on a real public available data set show that the method is accurate and competitive with some existing methods in the literature.
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U2 - 10.1109/DSAA.2015.7344836
DO - 10.1109/DSAA.2015.7344836
M3 - Conference contribution
AN - SCOPUS:84962920378
T3 - Proceedings of the 2015 IEEE International Conference on Data Science and Advanced Analytics, DSAA 2015
BT - Proceedings of the 2015 IEEE International Conference on Data Science and Advanced Analytics, DSAA 2015
A2 - Pasi, Gabriella
A2 - Kwok, James
A2 - Zaiane, Osmar
A2 - Gallinari, Patrick
A2 - Gaussier, Eric
A2 - Cao, Longbing
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - IEEE International Conference on Data Science and Advanced Analytics, DSAA 2015
Y2 - 19 October 2015 through 21 October 2015
ER -