Mri of pancreatic islet cell carcinoma

Blake Carlson, C. Daniel Johnson, David H. Stephens, Ellen M. Ward, Larry K. Kvols

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Objective: The purpose of this study is to report the spectrum of MR findings of pancreatic islet cell carcinoma. Materials and Methods: The MR scans of 33 patients with islet cell carcinoma were retrospectively reviewed. Magnetic resonance detected the primary tumor in 21 of 27 patients (78%) who had not had prior resection of their primary tumor. Mean tumor diameter was 7.1 cm (range 3.5-13.0 cm). Results: In all patients, the primary tumor on Tl-weighted images (TR/TE = 250/15) was of signal intensity equal to or lower than that of the adjacent normal pancreas. The primary tumor on T2-weighted images (TR/TE = 2, 000/ >100) was of signal intensity the same as or higher than fat in 18 of 21 patients (86%) and had mixed signal intensity in the other 3 (14%). Hepatic metastases were found in 28 of 33 patients (85%). Liver metastases were categorized as “usual” (variably circumscribed, homogeneous lesions of medium signal intensity on T2-weigh ted images) in 19 of 28 patients (68%), necrotic in 8 of 28 (29%), hemorrhagic in 3 of 28 (11%), and calcified in 1 of 28 (4%). Extrahepatic metastases were found in 18 of 33 patients (55%). Conclusion: We conclude that MRI is an excellent modality for the diagnosis and routine follow-up of patients with islet cell carcinoma.

Original languageEnglish (US)
Pages (from-to)735-740
Number of pages6
JournalJournal of Computer Assisted Tomography
Volume17
Issue number5
DOIs
StatePublished - Jan 1 1993

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Islet Cell Carcinoma
Islets of Langerhans
Neoplasms
Neoplasm Metastasis
Liver
Pancreas
Magnetic Resonance Spectroscopy
Fats

Keywords

  • Hemangioma
  • Liver
  • Magnetic resonance imaging
  • Neoplasms
  • Neoplasms
  • Pancreas

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Mri of pancreatic islet cell carcinoma. / Carlson, Blake; Johnson, C. Daniel; Stephens, David H.; Ward, Ellen M.; Kvols, Larry K.

In: Journal of Computer Assisted Tomography, Vol. 17, No. 5, 01.01.1993, p. 735-740.

Research output: Contribution to journalArticle

Carlson, Blake ; Johnson, C. Daniel ; Stephens, David H. ; Ward, Ellen M. ; Kvols, Larry K. / Mri of pancreatic islet cell carcinoma. In: Journal of Computer Assisted Tomography. 1993 ; Vol. 17, No. 5. pp. 735-740.
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abstract = "Objective: The purpose of this study is to report the spectrum of MR findings of pancreatic islet cell carcinoma. Materials and Methods: The MR scans of 33 patients with islet cell carcinoma were retrospectively reviewed. Magnetic resonance detected the primary tumor in 21 of 27 patients (78{\%}) who had not had prior resection of their primary tumor. Mean tumor diameter was 7.1 cm (range 3.5-13.0 cm). Results: In all patients, the primary tumor on Tl-weighted images (TR/TE = 250/15) was of signal intensity equal to or lower than that of the adjacent normal pancreas. The primary tumor on T2-weighted images (TR/TE = 2, 000/ >100) was of signal intensity the same as or higher than fat in 18 of 21 patients (86{\%}) and had mixed signal intensity in the other 3 (14{\%}). Hepatic metastases were found in 28 of 33 patients (85{\%}). Liver metastases were categorized as “usual” (variably circumscribed, homogeneous lesions of medium signal intensity on T2-weigh ted images) in 19 of 28 patients (68{\%}), necrotic in 8 of 28 (29{\%}), hemorrhagic in 3 of 28 (11{\%}), and calcified in 1 of 28 (4{\%}). Extrahepatic metastases were found in 18 of 33 patients (55{\%}). Conclusion: We conclude that MRI is an excellent modality for the diagnosis and routine follow-up of patients with islet cell carcinoma.",
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AB - Objective: The purpose of this study is to report the spectrum of MR findings of pancreatic islet cell carcinoma. Materials and Methods: The MR scans of 33 patients with islet cell carcinoma were retrospectively reviewed. Magnetic resonance detected the primary tumor in 21 of 27 patients (78%) who had not had prior resection of their primary tumor. Mean tumor diameter was 7.1 cm (range 3.5-13.0 cm). Results: In all patients, the primary tumor on Tl-weighted images (TR/TE = 250/15) was of signal intensity equal to or lower than that of the adjacent normal pancreas. The primary tumor on T2-weighted images (TR/TE = 2, 000/ >100) was of signal intensity the same as or higher than fat in 18 of 21 patients (86%) and had mixed signal intensity in the other 3 (14%). Hepatic metastases were found in 28 of 33 patients (85%). Liver metastases were categorized as “usual” (variably circumscribed, homogeneous lesions of medium signal intensity on T2-weigh ted images) in 19 of 28 patients (68%), necrotic in 8 of 28 (29%), hemorrhagic in 3 of 28 (11%), and calcified in 1 of 28 (4%). Extrahepatic metastases were found in 18 of 33 patients (55%). Conclusion: We conclude that MRI is an excellent modality for the diagnosis and routine follow-up of patients with islet cell carcinoma.

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