MRI-guided Wire Localization Surgical Biopsy in an Adolescent Patient with a Difficult to Diagnose Case of Lymphoma

Scott M. Thompson, Krzysztof R. Gorny, Danielle E. Jondal, Karen L. Rech, Samir Mardini, David A Woodrum

Research output: Contribution to journalArticle


A 17-year-old previously healthy female presented with a progressive soft tissue infiltrative process involving the neck and thorax. Extensive diagnostic evaluation including multiple imaging, laboratory, and biopsy studies was nondiagnostic. Due to an urgent need to establish a diagnosis and several previous nondiagnostic biopsies, she was referred to interventional radiology for MRI-guided wire localization immediately prior to open surgical biopsy. Under general anesthesia, wires were placed in the areas of increased T2 signal within the bilateral splenius capitis muscles using intermittent MRI-guidance followed by immediate surgical biopsy down to the wires. Pathology confirmed the diagnosis of diffuse large B-cell lymphoma.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalCardioVascular and Interventional Radiology
StateAccepted/In press - Sep 19 2016



  • Biopsy
  • Lymphoma
  • MRI-guided
  • Pediatric
  • Wire localization

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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