MRI-Guided Prostate Biopsy of Native and Recurrent Prostate Cancer

David A. Woodrum, Krzysztof R. Gorny, Bernadette Greenwood, Lance A. Mynderse

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Prostate cancer is the most commonly diagnosed noncutaneous cancer and second-leading cause of death in men. Many patients with clinically organ-confined prostate cancer undergo definitive, curative treatment of the whole gland with either radical prostatectomy or radiation therapy. However, many men are reluctant to take the definitive step due to potential morbidity associated with either therapy. A growing interest in active surveillance or focal therapy has emerged as realistic alternatives for many patients. With each of these management strategies, it is critical to accurately quantify and stage the cancer with improved biopsy targeting and more precise imaging with magnetic resonance imaging (MRI). Furthermore, having dependable prostate imaging allows for targeted biopsies to improve the yield of clinically significant prostate cancer and decrease detection of indolent prostate cancer. MRI-guided targeted biopsy techniques include cognitive MRI/transrectal ultrasound fusion biopsy, in-bore transrectal targeted biopsy using a calibrated guidance device, and in-bore direct MR-guided transperineal biopsy with a software-based transperineal grid template. Herein we present a contemporary review of MRI-guided targeted biopsy techniques for new and recurrent cancerous foci of the prostate.

Original languageEnglish (US)
Pages (from-to)196-205
Number of pages10
JournalSeminars in Interventional Radiology
Issue number3
StatePublished - Sep 1 2016


  • MRI
  • MRI targeted biopsy
  • interventional radiology
  • needle biopsy
  • prostate cancer

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'MRI-Guided Prostate Biopsy of Native and Recurrent Prostate Cancer'. Together they form a unique fingerprint.

Cite this