MRI, CT, and PET/CT for ovarian cancer detection and adnexal lesion characterization

Veena Iyer, Susanna I. Lee

Research output: Contribution to journalReview article

104 Citations (Scopus)

Abstract

OBJECTIVE. The purpose of this article is to describe the role of MR, CT, and PET/CT in the detection of ovarian cancer and the evaluation of adnexal lesions. CONCLUSION. The goal of imaging in ovarian cancer detection is to expeditiously distinguish benign adnexal lesions from those requiring further pathologic evaluation for malignancy. For lesions indeterminate on ultrasound, MRI increases the specificity of imaging evaluation, thus decreasing benign resections. CT is useful in diagnosis and treatment planning of advanced cancer. Although 18F-FDG-avid ovarian lesions in postmenopausal women are considered suspicious for malignancy, PET/CT is not recommended for primary cancer detection because of high false-positive rates.

Original languageEnglish (US)
Pages (from-to)311-321
Number of pages11
JournalAmerican Journal of Roentgenology
Volume194
Issue number2
DOIs
StatePublished - Feb 1 2010
Externally publishedYes

Fingerprint

Ovarian Neoplasms
Neoplasms
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography
Therapeutics

Keywords

  • Borderline tumor
  • Endometriosis
  • Gynecology
  • Krukenberg tumor
  • Screening
  • Staging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

MRI, CT, and PET/CT for ovarian cancer detection and adnexal lesion characterization. / Iyer, Veena; Lee, Susanna I.

In: American Journal of Roentgenology, Vol. 194, No. 2, 01.02.2010, p. 311-321.

Research output: Contribution to journalReview article

@article{08006a539d044f74923857a1eb4c5332,
title = "MRI, CT, and PET/CT for ovarian cancer detection and adnexal lesion characterization",
abstract = "OBJECTIVE. The purpose of this article is to describe the role of MR, CT, and PET/CT in the detection of ovarian cancer and the evaluation of adnexal lesions. CONCLUSION. The goal of imaging in ovarian cancer detection is to expeditiously distinguish benign adnexal lesions from those requiring further pathologic evaluation for malignancy. For lesions indeterminate on ultrasound, MRI increases the specificity of imaging evaluation, thus decreasing benign resections. CT is useful in diagnosis and treatment planning of advanced cancer. Although 18F-FDG-avid ovarian lesions in postmenopausal women are considered suspicious for malignancy, PET/CT is not recommended for primary cancer detection because of high false-positive rates.",
keywords = "Borderline tumor, Endometriosis, Gynecology, Krukenberg tumor, Screening, Staging",
author = "Veena Iyer and Lee, {Susanna I.}",
year = "2010",
month = "2",
day = "1",
doi = "10.2214/AJR.09.3522",
language = "English (US)",
volume = "194",
pages = "311--321",
journal = "American Journal of Roentgenology",
issn = "0361-803X",
publisher = "American Roentgen Ray Society",
number = "2",

}

TY - JOUR

T1 - MRI, CT, and PET/CT for ovarian cancer detection and adnexal lesion characterization

AU - Iyer, Veena

AU - Lee, Susanna I.

PY - 2010/2/1

Y1 - 2010/2/1

N2 - OBJECTIVE. The purpose of this article is to describe the role of MR, CT, and PET/CT in the detection of ovarian cancer and the evaluation of adnexal lesions. CONCLUSION. The goal of imaging in ovarian cancer detection is to expeditiously distinguish benign adnexal lesions from those requiring further pathologic evaluation for malignancy. For lesions indeterminate on ultrasound, MRI increases the specificity of imaging evaluation, thus decreasing benign resections. CT is useful in diagnosis and treatment planning of advanced cancer. Although 18F-FDG-avid ovarian lesions in postmenopausal women are considered suspicious for malignancy, PET/CT is not recommended for primary cancer detection because of high false-positive rates.

AB - OBJECTIVE. The purpose of this article is to describe the role of MR, CT, and PET/CT in the detection of ovarian cancer and the evaluation of adnexal lesions. CONCLUSION. The goal of imaging in ovarian cancer detection is to expeditiously distinguish benign adnexal lesions from those requiring further pathologic evaluation for malignancy. For lesions indeterminate on ultrasound, MRI increases the specificity of imaging evaluation, thus decreasing benign resections. CT is useful in diagnosis and treatment planning of advanced cancer. Although 18F-FDG-avid ovarian lesions in postmenopausal women are considered suspicious for malignancy, PET/CT is not recommended for primary cancer detection because of high false-positive rates.

KW - Borderline tumor

KW - Endometriosis

KW - Gynecology

KW - Krukenberg tumor

KW - Screening

KW - Staging

UR - http://www.scopus.com/inward/record.url?scp=76149115217&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76149115217&partnerID=8YFLogxK

U2 - 10.2214/AJR.09.3522

DO - 10.2214/AJR.09.3522

M3 - Review article

C2 - 20093590

AN - SCOPUS:76149115217

VL - 194

SP - 311

EP - 321

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

SN - 0361-803X

IS - 2

ER -