MR spectroscopy of cervical spinal cord in patients with multiple sclerosis

Ayşe Tuba Karagülle Kendi, Funda Uysal Tan, Mustafa Kendi, Sinef Huvaj, Serdar Tellioǧlu

Research output: Contribution to journalArticlepeer-review

67 Scopus citations

Abstract

MR spectroscopy (MRS) of the brain in patients with multiple sclerosis has been well studied. However, in vivo MRS of the spinal cord in patients with MR spectroscopy has not been reported to our knowledge. We performed MRS of normal-appearing cervical spinal cords in multiple sclerosis patients and in healthy controls. N-acetyl aspartate was shown to be reduced within the cervical spinal cord of multiple sclerosis patients when compared with healthy controls. This finding supports axonal loss and damage within even normal-appearing spinal cords of multiple sclerosis patients.

Original languageEnglish (US)
Pages (from-to)764-769
Number of pages6
JournalNeuroradiology
Volume46
Issue number9
DOIs
StatePublished - Sep 2004

Keywords

  • Magnetic resonance spectroscopy
  • Multiple sclerosis
  • Spinal cord

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

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