MR spectroscopy of cervical spinal cord in patients with multiple sclerosis

Ayşe Tuba Karagülle Kendi; Funda Uysal Tan; Mustafa Kendi; Sinef Huvaj; Serdar Tellioǧlu

doi:10.1007/s00234-004-1231-1

MR spectroscopy of cervical spinal cord in patients with multiple sclerosis

Ayşe Tuba Karagülle Kendi, Funda Uysal Tan, Mustafa Kendi, Sinef Huvaj, Serdar Tellioǧlu

Radiology

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

MR spectroscopy (MRS) of the brain in patients with multiple sclerosis has been well studied. However, in vivo MRS of the spinal cord in patients with MR spectroscopy has not been reported to our knowledge. We performed MRS of normal-appearing cervical spinal cords in multiple sclerosis patients and in healthy controls. N-acetyl aspartate was shown to be reduced within the cervical spinal cord of multiple sclerosis patients when compared with healthy controls. This finding supports axonal loss and damage within even normal-appearing spinal cords of multiple sclerosis patients.

Original language	English (US)
Pages (from-to)	764-769
Number of pages	6
Journal	Neuroradiology
Volume	46
Issue number	9
DOIs	https://doi.org/10.1007/s00234-004-1231-1
State	Published - Sep 2004

Keywords

Magnetic resonance spectroscopy
Multiple sclerosis
Spinal cord

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology
Cardiology and Cardiovascular Medicine

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10.1007/s00234-004-1231-1

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title = "MR spectroscopy of cervical spinal cord in patients with multiple sclerosis",

abstract = "MR spectroscopy (MRS) of the brain in patients with multiple sclerosis has been well studied. However, in vivo MRS of the spinal cord in patients with MR spectroscopy has not been reported to our knowledge. We performed MRS of normal-appearing cervical spinal cords in multiple sclerosis patients and in healthy controls. N-acetyl aspartate was shown to be reduced within the cervical spinal cord of multiple sclerosis patients when compared with healthy controls. This finding supports axonal loss and damage within even normal-appearing spinal cords of multiple sclerosis patients.",

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AU - Tan, Funda Uysal

AU - Kendi, Mustafa

AU - Huvaj, Sinef

AU - Tellioǧlu, Serdar

PY - 2004/9

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N2 - MR spectroscopy (MRS) of the brain in patients with multiple sclerosis has been well studied. However, in vivo MRS of the spinal cord in patients with MR spectroscopy has not been reported to our knowledge. We performed MRS of normal-appearing cervical spinal cords in multiple sclerosis patients and in healthy controls. N-acetyl aspartate was shown to be reduced within the cervical spinal cord of multiple sclerosis patients when compared with healthy controls. This finding supports axonal loss and damage within even normal-appearing spinal cords of multiple sclerosis patients.

AB - MR spectroscopy (MRS) of the brain in patients with multiple sclerosis has been well studied. However, in vivo MRS of the spinal cord in patients with MR spectroscopy has not been reported to our knowledge. We performed MRS of normal-appearing cervical spinal cords in multiple sclerosis patients and in healthy controls. N-acetyl aspartate was shown to be reduced within the cervical spinal cord of multiple sclerosis patients when compared with healthy controls. This finding supports axonal loss and damage within even normal-appearing spinal cords of multiple sclerosis patients.

KW - Magnetic resonance spectroscopy

KW - Multiple sclerosis

KW - Spinal cord

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MR spectroscopy of cervical spinal cord in patients with multiple sclerosis

Abstract

Keywords

ASJC Scopus subject areas

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