MR imaging and diffusion-weighted imaging changes in metronidazole (Flagyl)-induced cerebellar toxicity

Conor J. Heaney, Norbert G Campeau, E. Paul Lindell

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

We describe a case demonstrating reversible MR imaging findings, including diffusion-weighted imaging changes in association with metronidazole (Flagyl) toxicity. The diagnosis of metronidazole toxicity was made clinically and supported by the MR imaging findings. Quantitative apparent diffusion coefficient (ADC) maps demonstrated edema with associated increased ADC values within the dentate nuclei of the cerebellum on initial imaging. Follow-up imaging performed 8 weeks after cessation of metronidazole therapy demonstrated resolution of imaging findings, including diffusion changes.

Original languageEnglish (US)
Pages (from-to)1615-1617
Number of pages3
JournalAmerican Journal of Neuroradiology
Volume24
Issue number8
StatePublished - Sep 2003

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Metronidazole
Cerebellar Nuclei
Cerebellum
Edema
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

MR imaging and diffusion-weighted imaging changes in metronidazole (Flagyl)-induced cerebellar toxicity. / Heaney, Conor J.; Campeau, Norbert G; Lindell, E. Paul.

In: American Journal of Neuroradiology, Vol. 24, No. 8, 09.2003, p. 1615-1617.

Research output: Contribution to journalArticle

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