TY - JOUR
T1 - Moving fecal microbiota transplantation into the mainstream
AU - Orenstein, Robert
AU - Griesbach, Cheryl L.
AU - Dibaise, John K.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013/10
Y1 - 2013/10
N2 - In recent years, fecal microbiota transplantation (aka fecal transplantation, fecal bacteriotherapy, FMT) has become increasing utilized to treat recurrent and refractory Clostridium difficile infection (CDI). Almost 600,000 cases of CDI occur each year in the United States. Of these, an estimated 15,000 patients have a recurrence. The management of recurrent disease has been challenging for patients and clinicians. Increasingly, FMT has been recognized as an effective option for these patients. This article explores why FMT has reemerged as a practical therapeutic modality. In the process, the logistics by which the procedure is performed and the factors that may affect quality, safety, and patient outcomes will be described.
AB - In recent years, fecal microbiota transplantation (aka fecal transplantation, fecal bacteriotherapy, FMT) has become increasing utilized to treat recurrent and refractory Clostridium difficile infection (CDI). Almost 600,000 cases of CDI occur each year in the United States. Of these, an estimated 15,000 patients have a recurrence. The management of recurrent disease has been challenging for patients and clinicians. Increasingly, FMT has been recognized as an effective option for these patients. This article explores why FMT has reemerged as a practical therapeutic modality. In the process, the logistics by which the procedure is performed and the factors that may affect quality, safety, and patient outcomes will be described.
KW - Clostridium difficile metagenome
KW - fecal microbiota transplant
KW - fecal transplant
KW - microbiome
UR - http://www.scopus.com/inward/record.url?scp=84884322584&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884322584&partnerID=8YFLogxK
U2 - 10.1177/0884533613497516
DO - 10.1177/0884533613497516
M3 - Article
C2 - 23979974
AN - SCOPUS:84884322584
SN - 0884-5336
VL - 28
SP - 589
EP - 598
JO - Nutrition in Clinical Practice
JF - Nutrition in Clinical Practice
IS - 5
ER -