Mortality in hypereosinophilic syndrome

19 years of experience at Mayo Clinic with a review of the literature

Jenna C. Podjasek, Joseph H. Butterfield

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Background: Information in the literature regarding causes of mortality in patients with hypereosinophilic syndrome (HES) is limited. Methods: This was a retrospective review of the morbidities and causes of death in HES patients at Mayo Clinic. Results: Overall, out of the 247 diagnosed HES patients, 23 died during the 19 years that this review encompassed. The cause of death was identified in 15 patients (65%): cardiac dysfunction in 5 (33%), infection in 3 (20%), unrelated malignancy in 3 (20%), thromboembolic phenomena in 2 (13%), and vascular disease in 2 (13%). Conclusion: Targeted monitoring of the at-risk end organs, combined with early treatment, may have the ability to improve survival and reduce morbidity in HES patients.

Original languageEnglish (US)
Pages (from-to)392-395
Number of pages4
JournalLeukemia Research
Volume37
Issue number4
DOIs
StatePublished - Apr 2013

Fingerprint

Hypereosinophilic Syndrome
Mortality
Cause of Death
Organs at Risk
Morbidity
Vascular Diseases
Survival
Infection
Neoplasms

Keywords

  • Cause of death
  • Eosinophilia
  • Hypereosinophilia
  • Hypereosinophilic syndrome
  • Mortality

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology

Cite this

Mortality in hypereosinophilic syndrome : 19 years of experience at Mayo Clinic with a review of the literature. / Podjasek, Jenna C.; Butterfield, Joseph H.

In: Leukemia Research, Vol. 37, No. 4, 04.2013, p. 392-395.

Research output: Contribution to journalArticle

Podjasek, Jenna C. ; Butterfield, Joseph H. / Mortality in hypereosinophilic syndrome : 19 years of experience at Mayo Clinic with a review of the literature. In: Leukemia Research. 2013 ; Vol. 37, No. 4. pp. 392-395.
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