Abstract
Background: Information in the literature regarding causes of mortality in patients with hypereosinophilic syndrome (HES) is limited. Methods: This was a retrospective review of the morbidities and causes of death in HES patients at Mayo Clinic. Results: Overall, out of the 247 diagnosed HES patients, 23 died during the 19 years that this review encompassed. The cause of death was identified in 15 patients (65%): cardiac dysfunction in 5 (33%), infection in 3 (20%), unrelated malignancy in 3 (20%), thromboembolic phenomena in 2 (13%), and vascular disease in 2 (13%). Conclusion: Targeted monitoring of the at-risk end organs, combined with early treatment, may have the ability to improve survival and reduce morbidity in HES patients.
Original language | English (US) |
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Pages (from-to) | 392-395 |
Number of pages | 4 |
Journal | Leukemia Research |
Volume | 37 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2013 |
Keywords
- Cause of death
- Eosinophilia
- Hypereosinophilia
- Hypereosinophilic syndrome
- Mortality
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research