Morphology-guided radiotherapy treatment planning and optimization

Qingrong Wu, J. Daniel Bourland, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

In gamma unit radiosurgery treatment planning, dose delivery is based on the unit 'shot,' a distribution of dose approximately spherical in shape. Multiple shots are used to cover different parts of a given target region. Effective 3D optimization for gamma unit treatment has not been previously reported. In this article, a novel optimization method is introduced based on medial axis transformation techniques. Given a defined target volume, the target's medial axis, which uniquely characterizes the target, is used to determine the optimal shot positions and sizes. In using the medial axis, the 3D optimization problem is reduced to a 1D optimization, with corresponding savings in computational time and mathematical complexity. In addition, optimization based on target shape replicates and automates manual treatment planning, which makes the process easily understandable. Results of optimal plans and the corresponding dose distributions are presented. The relationship between skeleton disks and the dose distributions they predict are also discussed.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsYongmin Kim
Pages180-189
Number of pages10
Volume2707
StatePublished - 1996
EventMedical Imaging 1996: Image Display - Newport Beach, CA, USA
Duration: Feb 11 1996Feb 13 1996

Other

OtherMedical Imaging 1996: Image Display
CityNewport Beach, CA, USA
Period2/11/962/13/96

Fingerprint

Radiotherapy
planning
radiation therapy
Medial Axis
Planning
Dose
optimization
Target
Optimization
shot
dosage
Unit
Skeleton
musculoskeletal system
Optimization Methods
delivery
Cover
Optimization Problem
Predict

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics
  • Applied Mathematics
  • Computer Science Applications
  • Electronic, Optical and Magnetic Materials

Cite this

Wu, Q., Bourland, J. D., & Robb, R. A. (1996). Morphology-guided radiotherapy treatment planning and optimization. In Y. Kim (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2707, pp. 180-189)

Morphology-guided radiotherapy treatment planning and optimization. / Wu, Qingrong; Bourland, J. Daniel; Robb, Richard A.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Yongmin Kim. Vol. 2707 1996. p. 180-189.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wu, Q, Bourland, JD & Robb, RA 1996, Morphology-guided radiotherapy treatment planning and optimization. in Y Kim (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 2707, pp. 180-189, Medical Imaging 1996: Image Display, Newport Beach, CA, USA, 2/11/96.
Wu Q, Bourland JD, Robb RA. Morphology-guided radiotherapy treatment planning and optimization. In Kim Y, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2707. 1996. p. 180-189
Wu, Qingrong ; Bourland, J. Daniel ; Robb, Richard A. / Morphology-guided radiotherapy treatment planning and optimization. Proceedings of SPIE - The International Society for Optical Engineering. editor / Yongmin Kim. Vol. 2707 1996. pp. 180-189
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