Morphologic Subtypes of Hepatocellular Carcinoma

Michael S. Torbenson

doi:10.1016/j.gtc.2017.01.009

Morphologic Subtypes of Hepatocellular Carcinoma

Michael S. Torbenson

Laboratory Medicine and Pathology

Research output: Contribution to journal › Review article › peer-review

35 Scopus citations

Abstract

Hepatocellular carcinomas can be further divided into distinct subtypes that provide important clinical information and biological insights. These subtypes are distinct from growth patterns and are on based on morphologic and molecular findings. There are 12 reasonably well-defined subtypes as well as 6 provisional subtypes, together making up 35% of all hepatocellular carcinomas. These subtypes are discussed, with an emphasis on their definitions and the key morphologic findings.

Original language	English (US)
Pages (from-to)	365-391
Number of pages	27
Journal	Gastroenterology Clinics of North America
Volume	46
Issue number	2
DOIs	https://doi.org/10.1016/j.gtc.2017.01.009
State	Published - Jun 2017

Keywords

Carcinosarcoma
Cirrhotomimetic hepatocellular carcinoma
Clear cell hepatocellular carcinoma
Diffuse hepatocellular carcinoma
Fibrolamellar carcinoma
Hepatocellular carcinoma subtypes
Sarcomatoid hepatocellular carcinoma
Scirrhous hepatocellular carcinoma

ASJC Scopus subject areas

Gastroenterology

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10.1016/j.gtc.2017.01.009

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title = "Morphologic Subtypes of Hepatocellular Carcinoma",

abstract = "Hepatocellular carcinomas can be further divided into distinct subtypes that provide important clinical information and biological insights. These subtypes are distinct from growth patterns and are on based on morphologic and molecular findings. There are 12 reasonably well-defined subtypes as well as 6 provisional subtypes, together making up 35% of all hepatocellular carcinomas. These subtypes are discussed, with an emphasis on their definitions and the key morphologic findings.",

keywords = "Carcinosarcoma, Cirrhotomimetic hepatocellular carcinoma, Clear cell hepatocellular carcinoma, Diffuse hepatocellular carcinoma, Fibrolamellar carcinoma, Hepatocellular carcinoma subtypes, Sarcomatoid hepatocellular carcinoma, Scirrhous hepatocellular carcinoma",

author = "Torbenson, {Michael S.}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2017",

month = jun,

doi = "10.1016/j.gtc.2017.01.009",

language = "English (US)",

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journal = "Gastroenterology Clinics of North America",

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T1 - Morphologic Subtypes of Hepatocellular Carcinoma

AU - Torbenson, Michael S.

PY - 2017/6

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N2 - Hepatocellular carcinomas can be further divided into distinct subtypes that provide important clinical information and biological insights. These subtypes are distinct from growth patterns and are on based on morphologic and molecular findings. There are 12 reasonably well-defined subtypes as well as 6 provisional subtypes, together making up 35% of all hepatocellular carcinomas. These subtypes are discussed, with an emphasis on their definitions and the key morphologic findings.

AB - Hepatocellular carcinomas can be further divided into distinct subtypes that provide important clinical information and biological insights. These subtypes are distinct from growth patterns and are on based on morphologic and molecular findings. There are 12 reasonably well-defined subtypes as well as 6 provisional subtypes, together making up 35% of all hepatocellular carcinomas. These subtypes are discussed, with an emphasis on their definitions and the key morphologic findings.

KW - Carcinosarcoma

KW - Cirrhotomimetic hepatocellular carcinoma

KW - Clear cell hepatocellular carcinoma

KW - Diffuse hepatocellular carcinoma

KW - Fibrolamellar carcinoma

KW - Hepatocellular carcinoma subtypes

KW - Sarcomatoid hepatocellular carcinoma

KW - Scirrhous hepatocellular carcinoma

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U2 - 10.1016/j.gtc.2017.01.009

DO - 10.1016/j.gtc.2017.01.009

M3 - Review article

C2 - 28506370

AN - SCOPUS:85019182287

SN - 0889-8553

VL - 46

SP - 365

EP - 391

JO - Gastroenterology Clinics of North America

JF - Gastroenterology Clinics of North America

IS - 2

ER -

Morphologic Subtypes of Hepatocellular Carcinoma

Abstract

Keywords

ASJC Scopus subject areas

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