The genetics of the motor neuron diseases are becoming increasingly important. The relationship of primary lateral sclerosis and amyotrophic lateral sclerosis remains debated. Here a pair of monozygotic twins discordant for primary lateral sclerosis is presented. This monozygotic twin pair suggests that environmental factors were most relevant to this subject's development of primary lateral sclerosis. Their life history suggests very similar social and professional exposures without any apparent distinctions.
- Amyotrophic lateral sclerosis
- Primary lateral sclerosis
ASJC Scopus subject areas
- Clinical Neurology