Monoclonal gammopathy of undetermined significance

Robert A. Kyle, S Vincent Rajkumar

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Monoclonal gammopathy of undetermined significance (MGUS) is defined by a monoclonal immunoglobulin in serum of <3 g/dL, fewer than 10% plasma cells in the bone marrow and no evidence of lytic bone lesions, anemia, hypercalcemia, or renal insufficiency related to the plasma cell proliferative process. More than 50% of patients with a monoclonal gammopathy at Mayo Clinic have MGUS. IgG is the most common type of M protein.

Original languageEnglish (US)
Title of host publicationMultiple Myeloma
Subtitle of host publicationTranslational and Emerging Therapies
PublisherCRC Press
Pages95-114
Number of pages20
ISBN (Electronic)9781420045116
ISBN (Print)9781420045109
StatePublished - Jan 1 2007

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Monoclonal Gammopathy of Undetermined Significance
Plasma Cells
Paraproteinemias
Hypercalcemia
Renal Insufficiency
Immunoglobulins
Anemia
Immunoglobulin G
Bone Marrow
Bone and Bones
Serum
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kyle, R. A., & Rajkumar, S. V. (2007). Monoclonal gammopathy of undetermined significance. In Multiple Myeloma: Translational and Emerging Therapies (pp. 95-114). CRC Press.

Monoclonal gammopathy of undetermined significance. / Kyle, Robert A.; Rajkumar, S Vincent.

Multiple Myeloma: Translational and Emerging Therapies. CRC Press, 2007. p. 95-114.

Research output: Chapter in Book/Report/Conference proceedingChapter

Kyle, RA & Rajkumar, SV 2007, Monoclonal gammopathy of undetermined significance. in Multiple Myeloma: Translational and Emerging Therapies. CRC Press, pp. 95-114.
Kyle RA, Rajkumar SV. Monoclonal gammopathy of undetermined significance. In Multiple Myeloma: Translational and Emerging Therapies. CRC Press. 2007. p. 95-114
Kyle, Robert A. ; Rajkumar, S Vincent. / Monoclonal gammopathy of undetermined significance. Multiple Myeloma: Translational and Emerging Therapies. CRC Press, 2007. pp. 95-114
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