Monoclonal gammopathy of undetermined significance

Robert A. Kyle, S. Vincent Rajkumar

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Monoclonal gammopathy of undetermined significance (MGUS) is defined by a monoclonal immunoglobulin in serum of <3 g/dL, fewer than 10% plasma cells in the bone marrow and no evidence of lytic bone lesions, anemia, hypercalcemia, or renal insufficiency related to the plasma cell proliferative process. More than 50% of patients with a monoclonal gammopathy at Mayo Clinic have MGUS. IgG is the most common type of M protein.

Original languageEnglish (US)
Title of host publicationMultiple Myeloma
Subtitle of host publicationTranslational and Emerging Therapies
PublisherCRC Press
Pages95-114
Number of pages20
ISBN (Electronic)9781420045116
ISBN (Print)9781420045109
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • General Medicine

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