Molecular Pathogenesis of Infective Endocarditis

Cassandra L. Brinkman, Robin Patel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter focuses on infective endocarditis, specifically on the formation of vegetations, adherence of bacterial cells to damaged heart valves and their entry into mammalian cells. Emphasis is placed on those organisms that are common causative pathogens of endocarditis, including Staphylococcus aureus, viridans group streptococci and Enterococcus faecalis. In addition, this chapter concentrates on specific adherence molecules and virulence factors that play a critical role in infective endocarditis and are most commonly associated with the organisms mentioned above. Candida species are also briefly discussed as the incidence of these infections, as well as research on them, has increased in recent years.

Original languageEnglish (US)
Title of host publicationMolecular Medical Microbiology: Second Edition
PublisherElsevier Ltd
Pages811-822
Number of pages12
Volume2-3
ISBN (Print)9780123971692, 9780126775303
DOIs
StatePublished - Nov 26 2014

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Keywords

  • Adherence
  • Candida
  • Endocarditis
  • Enterococcus faecalis
  • Infection
  • Staphylococcus aureus
  • Viridans group streptococci
  • Virulence

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Brinkman, C. L., & Patel, R. (2014). Molecular Pathogenesis of Infective Endocarditis. In Molecular Medical Microbiology: Second Edition (Vol. 2-3, pp. 811-822). Elsevier Ltd. https://doi.org/10.1016/B978-0-12-397169-2.00044-5