Abstract
This chapter summarizes the significance and molecular diagnostic detection of genetic abnormalities commonly associated with hematolymphoid neoplasms. Methodologic aspects of laboratory diagnosis are presented, as well as discussion of multiparameter genotyping of tumors for prognosis and the role of minimal residual disease monitoring in specific neoplasms.
Original language | English (US) |
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Pages (from-to) | 903-933 |
Number of pages | 31 |
Journal | Hematology/Oncology Clinics of North America |
Volume | 23 |
Issue number | 4 |
DOIs | |
State | Published - Aug 2009 |
Keywords
- Chromosome translocation
- Clonality
- Fluorescence in situ hybridization
- Gene rearrangements
- Minimal residual disease
- Polymerase chain reaction
ASJC Scopus subject areas
- Hematology
- Oncology