Molecular Diagnosis of Hematopoietic and Lymphoid Neoplasms

Dragan Jevremovic, David S. Viswanatha

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

This chapter summarizes the significance and molecular diagnostic detection of genetic abnormalities commonly associated with hematolymphoid neoplasms. Methodologic aspects of laboratory diagnosis are presented, as well as discussion of multiparameter genotyping of tumors for prognosis and the role of minimal residual disease monitoring in specific neoplasms.

Original languageEnglish (US)
Pages (from-to)903-933
Number of pages31
JournalHematology/Oncology Clinics of North America
Volume23
Issue number4
DOIs
StatePublished - Aug 1 2009

Keywords

  • Chromosome translocation
  • Clonality
  • Fluorescence in situ hybridization
  • Gene rearrangements
  • Minimal residual disease
  • Polymerase chain reaction

ASJC Scopus subject areas

  • Hematology
  • Oncology

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