Molecular biology and gene transfer in atherosclerosis in the stenting era

N. M. Caplice, R. D. Simari, David Holmes

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Atherosclerosis is the major cause of death in the developed world. Understanding the pathogenesis of atherosclerosis has been a major challenge to cardiovascular research over the past several decades. During this period a number of advances in various scientific disciplines has increased our understanding of this disease. These include improved understanding of the structural and functional components of normal vessel wall and more recently the use of cell biology and molecular biology techniques to elucidate the pathogenesis of atherosclerosis. None of these advances has been more dramatic nor has potentially more far reaching consequences as the application of molecular biology and gene technology to the practice of cardiovascular medicine. These developments have already opened new and exciting areas of vascular research and may in the future provide for earlier identification of genetic predisposition to atherosclerosis, strategic planning of preventive therapy and more tailored pharmacologic approaches for established disease.

Original languageEnglish (US)
Pages (from-to)141-152
Number of pages12
JournalInternational Journal of Cardiovascular Interventions
Volume2
Issue number3
StatePublished - 1999

Fingerprint

Molecular Biology
Atherosclerosis
Genes
Genetic Predisposition to Disease
Research
Blood Vessels
Cell Biology
Cause of Death
Medicine
Technology
Therapeutics

Keywords

  • Atherosclerosis
  • Gene-transfer
  • Molecular biology

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Molecular biology and gene transfer in atherosclerosis in the stenting era. / Caplice, N. M.; Simari, R. D.; Holmes, David.

In: International Journal of Cardiovascular Interventions, Vol. 2, No. 3, 1999, p. 141-152.

Research output: Contribution to journalArticle

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