Abstract
Transfection of C3H/10T1/2 cells with a c-myc gene resulted in the acquisition of responsiveness to transforming growth factor type beta. Cells transfected with an activated H-ras gene or an H-ras and c-myc gene, however, exhibited a transformed morphology and spontaneous soft-agar growth, a phenotype induced reversibly by transforming growth factor type beta in responsive fibroblasts.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2649-2652 |
| Number of pages | 4 |
| Journal | Molecular and cellular biology |
| Volume | 7 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1987 |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology