Modular headache theory

W. B. Young, M. F.P. Peres, Todd Rozen

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Many people experience headaches that do not fulfil the International Headache Society's criteria for a specific headache disorder yet behave biologically like that disorder. Others fulfil criteria for one headache disorder and yet have features of another disorder. To explain these observations, we propose that groups of neurones called modules become activated to produce each symptom of a primary headache disorder, and that each module is linked to other modules that together produce an individual's headache. This theory has implications for the classification, research and treatment of primary and secondary headache patients.

Original languageEnglish (US)
Pages (from-to)842-849
Number of pages8
JournalCephalalgia
Volume21
Issue number8
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

Fingerprint

Headache
Headache Disorders
Primary Headache Disorders
Neurons
Research
Therapeutics

Keywords

  • Chronic paroxysmal hemicrania
  • Cluster headache
  • Headache
  • Hemicrania continua
  • Migraine
  • Pathophysiology
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Modular headache theory. / Young, W. B.; Peres, M. F.P.; Rozen, Todd.

In: Cephalalgia, Vol. 21, No. 8, 01.01.2001, p. 842-849.

Research output: Contribution to journalArticle

Young, WB, Peres, MFP & Rozen, T 2001, 'Modular headache theory', Cephalalgia, vol. 21, no. 8, pp. 842-849. https://doi.org/10.1046/j.1468-2982.2001.218254.x
Young, W. B. ; Peres, M. F.P. ; Rozen, Todd. / Modular headache theory. In: Cephalalgia. 2001 ; Vol. 21, No. 8. pp. 842-849.
@article{75ae911fd5524b679c28917ee109f2f9,
title = "Modular headache theory",
abstract = "Many people experience headaches that do not fulfil the International Headache Society's criteria for a specific headache disorder yet behave biologically like that disorder. Others fulfil criteria for one headache disorder and yet have features of another disorder. To explain these observations, we propose that groups of neurones called modules become activated to produce each symptom of a primary headache disorder, and that each module is linked to other modules that together produce an individual's headache. This theory has implications for the classification, research and treatment of primary and secondary headache patients.",
keywords = "Chronic paroxysmal hemicrania, Cluster headache, Headache, Hemicrania continua, Migraine, Pathophysiology, Trigeminal neuralgia",
author = "Young, {W. B.} and Peres, {M. F.P.} and Todd Rozen",
year = "2001",
month = "1",
day = "1",
doi = "10.1046/j.1468-2982.2001.218254.x",
language = "English (US)",
volume = "21",
pages = "842--849",
journal = "Cephalalgia",
issn = "0333-1024",
publisher = "SAGE Publications Ltd",
number = "8",

}

TY - JOUR

T1 - Modular headache theory

AU - Young, W. B.

AU - Peres, M. F.P.

AU - Rozen, Todd

PY - 2001/1/1

Y1 - 2001/1/1

N2 - Many people experience headaches that do not fulfil the International Headache Society's criteria for a specific headache disorder yet behave biologically like that disorder. Others fulfil criteria for one headache disorder and yet have features of another disorder. To explain these observations, we propose that groups of neurones called modules become activated to produce each symptom of a primary headache disorder, and that each module is linked to other modules that together produce an individual's headache. This theory has implications for the classification, research and treatment of primary and secondary headache patients.

AB - Many people experience headaches that do not fulfil the International Headache Society's criteria for a specific headache disorder yet behave biologically like that disorder. Others fulfil criteria for one headache disorder and yet have features of another disorder. To explain these observations, we propose that groups of neurones called modules become activated to produce each symptom of a primary headache disorder, and that each module is linked to other modules that together produce an individual's headache. This theory has implications for the classification, research and treatment of primary and secondary headache patients.

KW - Chronic paroxysmal hemicrania

KW - Cluster headache

KW - Headache

KW - Hemicrania continua

KW - Migraine

KW - Pathophysiology

KW - Trigeminal neuralgia

UR - http://www.scopus.com/inward/record.url?scp=0035740825&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035740825&partnerID=8YFLogxK

U2 - 10.1046/j.1468-2982.2001.218254.x

DO - 10.1046/j.1468-2982.2001.218254.x

M3 - Article

C2 - 11737011

AN - SCOPUS:0035740825

VL - 21

SP - 842

EP - 849

JO - Cephalalgia

JF - Cephalalgia

SN - 0333-1024

IS - 8

ER -