Modified histologic technique for processing metallic coil-bearing tissue

Daying Dai, Yong Hong Ding, Mark A. Danielson, Ramanathan Kadirvel, Debra A. Lewis, Harry J. Cloft, David F. Kallmes

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

We developed a modified paraffin embedding histologic technique for processing metallic coil-bearing aneurysm tissues. This modified technique was successfully employed for processing platinum coil-bearing tissue for 30 rabbit aneurysms and 6 swine aneurysms. This technique for sectioning coil-bearing aneurysms resulted in little or no tissue distortion and permitted good preservation of morphology and application of multiple advanced staining techniques. This technique is considered beneficial for studying the molecular mechanisms of aneurysm healing after coiling.

Original languageEnglish (US)
Pages (from-to)1932-1936
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume26
Issue number8
StatePublished - Dec 1 2005

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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