Modern histological classification of low grade B-cell lymphomas

Ahmet Dogan

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

The classification of lymphomas has been one of the most controversial areas of tumour pathology. Most of the difficulties in development of sophisticated classifications have been a direct consequence of the biological diversity inherent in this group of neoplasms; a reflection of the physiological complexity of lymphocyte development and differentiation. The new World Health Organisation (WHO) lymphoma classification identifies individual clinicopathological entities; integrating morphology, immunophenotype, genotype, normal cell counterpart/cell of origin and clinical features. The degree to which these five characteristics contributes to the definition of individual entities differs from one entity to the other. This classification has received worldwide acceptance in the short term it has been available and has become the gold standard in lymphoma diagnosis.

Original languageEnglish (US)
Pages (from-to)11-26
Number of pages16
JournalBest Practice and Research: Clinical Haematology
Volume18
Issue number1 SPEC. ISS.
DOIs
StatePublished - Mar 2005

Keywords

  • B-cell
  • Classification
  • Low-grade
  • Lymphoma
  • WHO

ASJC Scopus subject areas

  • Oncology
  • Clinical Biochemistry

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