Modeling of radiofrequency ablation lesions for image-guided arrhythmia therapy: A preliminary ex vivo demonstration

Cristian A. Linte, Jon J. Camp, David R. Holmes, Maryam E. Rettmann, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

In spite of significant efforts to enhance guidance for catheter navigation, very little has been done to consider the changes that occur in the tissue during ablation as a means to provide feedback on therapy delivery. We propose a technique to visualize the lesion progression and monitor the RF energy delivery by means of a real-time thermal ablation model. The model is based on physical and physiological tissue parameters, and uses heat transfer principles to estimate temperature distribution and geometry of the generated lesion in real time. Validation of the model against experimental measurements recorded in ex vivo muscle samples ablated under clinically relevant conditions demonstrated good agreement between the predicted and measured parameters. We believe this technique will enable the generation of real-time thermal maps that can be used to guide the placement of successive lesions to ensure continuous and effective suppression of the arrhythmic pathway.

Original languageEnglish (US)
Title of host publicationAugmented Environments for Computer-Assisted Interventions - 7th International Workshop, AE-CAI 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers
Pages22-33
Number of pages12
DOIs
StatePublished - Oct 23 2013
Event7th International Workshop on Augmented Environments for Computer-Assisted Interventions, AE-CAI 2012, Held in Conjunction with MICCAI 2012 - Nice, France
Duration: Oct 5 2013Oct 5 2013

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume7815 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other7th International Workshop on Augmented Environments for Computer-Assisted Interventions, AE-CAI 2012, Held in Conjunction with MICCAI 2012
CountryFrance
CityNice
Period10/5/1310/5/13

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ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Cite this

Linte, C. A., Camp, J. J., Holmes, D. R., Rettmann, M. E., & Robb, R. A. (2013). Modeling of radiofrequency ablation lesions for image-guided arrhythmia therapy: A preliminary ex vivo demonstration. In Augmented Environments for Computer-Assisted Interventions - 7th International Workshop, AE-CAI 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers (pp. 22-33). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 7815 LNCS). https://doi.org/10.1007/978-3-642-38085-3_4