Mitral valve repair: MitraClip and emerging techniques

Ted Feldman, Mohammad Sarraf, Mayra Guerrero, Francesco Maisano

Research output: Chapter in Book/Report/Conference proceedingChapter


Percutaneous mitral valve repair has emerged as an alternative to surgery for patients with significant symptomatic mitral regurgitation (MR) and prohibitive risk for surgical mitral repair or replacement. The MitraClip system consists of three major components: a 24-Fr steerable guiding catheter, the clip delivery system (CDS), and the MitraClip device. The first MR surgical treatment concept to be adapted for percutaneous use was the double-orifice or edge-to-edge repair. The edge-to-edge repair concept led to the development of the MitraClip. This device replicates the surgical repair by mechanically grasping the mitral leaflet free edges. Transcatheter mitral valve replacement (TMVR) as a therapy for functional mitral regurgitation (FMR) is also developing, with several different devices having first in human experience in the last 2 years. Transcatheter mitral repair and replacement interventions will become complementary solutions to accommodate the variability of the disease.

Original languageEnglish (US)
Title of host publicationInterventional Cardiology
Subtitle of host publicationPrinciples and Practice
Number of pages7
ISBN (Electronic)9781118983652
ISBN (Print)9781118976036
StatePublished - Nov 21 2016


  • Clip delivery system
  • Edge-to-edge repair
  • Mitraclip system
  • Mitral regurgitation
  • Percutaneous mitral valve repair
  • Surgical mitral repair
  • Transcatheter mitral valve replacement

ASJC Scopus subject areas

  • Medicine(all)


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