Abstract
Percutaneous mitral valve repair has emerged as an alternative to surgery for patients with significant symptomatic mitral regurgitation (MR) and prohibitive risk for surgical mitral repair or replacement. The MitraClip system consists of three major components: a 24-Fr steerable guiding catheter, the clip delivery system (CDS), and the MitraClip device. The first MR surgical treatment concept to be adapted for percutaneous use was the double-orifice or edge-to-edge repair. The edge-to-edge repair concept led to the development of the MitraClip. This device replicates the surgical repair by mechanically grasping the mitral leaflet free edges. Transcatheter mitral valve replacement (TMVR) as a therapy for functional mitral regurgitation (FMR) is also developing, with several different devices having first in human experience in the last 2 years. Transcatheter mitral repair and replacement interventions will become complementary solutions to accommodate the variability of the disease.
Original language | English (US) |
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Title of host publication | Interventional Cardiology |
Subtitle of host publication | Principles and Practice |
Publisher | wiley |
Pages | 599-605 |
Number of pages | 7 |
ISBN (Electronic) | 9781118983652 |
ISBN (Print) | 9781118976036 |
DOIs | |
State | Published - Nov 21 2016 |
Keywords
- Clip delivery system
- Edge-to-edge repair
- Mitraclip system
- Mitral regurgitation
- Percutaneous mitral valve repair
- Surgical mitral repair
- Transcatheter mitral valve replacement
ASJC Scopus subject areas
- Medicine(all)