Mitral valve gradient after valve repair of degenerative regurgitation with restrictive annuloplasty

Backgrounds Outcomes of mitral valve repair have been well described for patients with degenerative regurgitation. The hemodynamic effects of repair have not been as well studied, however. We report hemodynamic outcomes in these patients. Methods We reviewed 1147 patients who underwent isolated mitral valve repair for degenerative mitral valve regurgitation between January 2004 and December 2013. Baseline characteristics included mean age 58.6 ± 13.4 years, male sex in 792 patients (69.1%), mean ejection fraction of 0.64 ± 0.07, and New York Heart Association class III/IV dyspnea in 215 patients (18.8%). Results Mitral valve repair involved the posterior leaflet in 764 patients (66.6%), anterior leaflet in 57 patients (5.0%), both leaflets in 260 patients (22.7%), and annuloplasty alone in 66 patients (5.8%). Among the patients who underwent posterior leaflet repair, 713 (93.3%) were treated with our standard technique of triangular leaflet resection/plication and repair with partial posterior band annuloplasty using an unmeasured 63-mm flexible band. Follow-up echocardiography data were obtained in 1138 survivors (99.4%) at 600 ± 880 days. Mild or less valve regurgitation was present at last follow-up in 1030 patients (90.5%). The mean mitral valve gradient was 3.1 ± 1.4 mm Hg in the operating room and 3.5 ± 1.6 mm Hg at the last follow-up (P <.001). The mean mitral valve gradient decreased from the first to the second median time periods (124.5 days) of follow-up (3.7 ± 1.6 mm Hg to 3.3 ± 1.8 mm Hg; P <.001). Conclusions Mitral valve repair for degenerative regurgitation results in a small mitral valve gradient that appears to decrease with time after discharge.