MitraClip Therapy for Mitral Regurgitation: Secondary Mitral Regurgitation

Ted Feldman; Arjun Mehta; Mayra Guerrero; Justin P. Levisay; Michael H. Salinger

doi:10.1016/j.iccl.2015.08.007

MitraClip Therapy for Mitral Regurgitation: Secondary Mitral Regurgitation

Ted Feldman, Arjun Mehta, Mayra Guerrero, Justin P. Levisay, Michael H. Salinger

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Abstract

Therapy for mitral regurgitation (MR) has been synonymous with mitral valve surgery. Operative approaches for degenerative MR repair have been associated with excellent results, with durable long term outcomes. Surgery for functional MR has been less successful. MitraClip has shown promise for functional MR, especiall in patinets who are high risk for surgery. The aggregate of nonrandomized global experience with MitraClip in functional MR has been consistent in showing improvements in symptoms and left ventricular remodeling. It remains to be seen how MitraClip therapy will compare with best medical therapy. The COAPT trial will clarify this question.

Original language	English (US)
Pages (from-to)	83-91
Number of pages	9
Journal	Interventional Cardiology Clinics
Volume	5
Issue number	1
DOIs	https://doi.org/10.1016/j.iccl.2015.08.007
State	Published - Jan 1 2016
Externally published	Yes

Keywords

COAPT
Functional mitral regurgitation
MitraClip
Mitral regurgitation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/j.iccl.2015.08.007

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Cite this

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title = "MitraClip Therapy for Mitral Regurgitation: Secondary Mitral Regurgitation",

abstract = "Therapy for mitral regurgitation (MR) has been synonymous with mitral valve surgery. Operative approaches for degenerative MR repair have been associated with excellent results, with durable long term outcomes. Surgery for functional MR has been less successful. MitraClip has shown promise for functional MR, especiall in patinets who are high risk for surgery. The aggregate of nonrandomized global experience with MitraClip in functional MR has been consistent in showing improvements in symptoms and left ventricular remodeling. It remains to be seen how MitraClip therapy will compare with best medical therapy. The COAPT trial will clarify this question.",

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AU - Mehta, Arjun

AU - Guerrero, Mayra

AU - Levisay, Justin P.

AU - Salinger, Michael H.

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AB - Therapy for mitral regurgitation (MR) has been synonymous with mitral valve surgery. Operative approaches for degenerative MR repair have been associated with excellent results, with durable long term outcomes. Surgery for functional MR has been less successful. MitraClip has shown promise for functional MR, especiall in patinets who are high risk for surgery. The aggregate of nonrandomized global experience with MitraClip in functional MR has been consistent in showing improvements in symptoms and left ventricular remodeling. It remains to be seen how MitraClip therapy will compare with best medical therapy. The COAPT trial will clarify this question.

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