TY - JOUR
T1 - MitraClip Therapy for Mitral Regurgitation
T2 - Secondary Mitral Regurgitation
AU - Feldman, Ted
AU - Mehta, Arjun
AU - Guerrero, Mayra
AU - Levisay, Justin P.
AU - Salinger, Michael H.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Therapy for mitral regurgitation (MR) has been synonymous with mitral valve surgery. Operative approaches for degenerative MR repair have been associated with excellent results, with durable long term outcomes. Surgery for functional MR has been less successful. MitraClip has shown promise for functional MR, especiall in patinets who are high risk for surgery. The aggregate of nonrandomized global experience with MitraClip in functional MR has been consistent in showing improvements in symptoms and left ventricular remodeling. It remains to be seen how MitraClip therapy will compare with best medical therapy. The COAPT trial will clarify this question.
AB - Therapy for mitral regurgitation (MR) has been synonymous with mitral valve surgery. Operative approaches for degenerative MR repair have been associated with excellent results, with durable long term outcomes. Surgery for functional MR has been less successful. MitraClip has shown promise for functional MR, especiall in patinets who are high risk for surgery. The aggregate of nonrandomized global experience with MitraClip in functional MR has been consistent in showing improvements in symptoms and left ventricular remodeling. It remains to be seen how MitraClip therapy will compare with best medical therapy. The COAPT trial will clarify this question.
KW - COAPT
KW - Functional mitral regurgitation
KW - MitraClip
KW - Mitral regurgitation
UR - http://www.scopus.com/inward/record.url?scp=84947585249&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84947585249&partnerID=8YFLogxK
U2 - 10.1016/j.iccl.2015.08.007
DO - 10.1016/j.iccl.2015.08.007
M3 - Review article
C2 - 27852484
AN - SCOPUS:84947585249
VL - 5
SP - 83
EP - 91
JO - Interventional Cardiology Clinics
JF - Interventional Cardiology Clinics
SN - 2211-7458
IS - 1
ER -