Abstract
Decreased expression of miRNAs of the miR-200 family has been implicated in the growth and metastasis of breast cancer cells. Of this family, miR-200c has garnered particular attention as a consequence of its ability to target ZEB1 and ZEB2, mediators of epithelial- mesenchymal transition. An article in the previous issue of Breast Cancer Research identifies additional targets of miR-200c that link increased cancer cell invasiveness, resistance to apoptosis, and induction of breast cancer stem cell characteristics.
Original language | English (US) |
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Article number | 110 |
Journal | Breast Cancer Research |
Volume | 13 |
Issue number | 3 |
DOIs | |
State | Published - Jun 10 2011 |
ASJC Scopus subject areas
- Oncology
- Cancer Research