Migrainous infarction of the eye: Two cases of monocular ischemic complications associated with retinal migraine

Nikita Chhabra, Chia Chun Chiang, Marie A. Di Nome, Odette Houghton, Rachel E. Carlin, Cumara B. O’Carroll, David W. Dodick, Oana M. Dumitrascu

Research output: Contribution to journalArticlepeer-review


Background: Retinal migraine is defined by fully reversible monocular visual phenomena. We present two cases that were complicated by permanent monocular vision deficits. Cases: A 57-year-old man with history of retinal migraine experienced persistent monocular vision loss after one stereotypical retinal migraine, progressing to finger-count vision over 4 days. He developed paracentral acute middle maculopathy that progressed to central retinal artery occlusion. A 27-year-old man with history of retinal migraine presented with persistent right eye superotemporal scotoma after a retinal migraine. Relative afferent pupillary defect and superotemporal visual field defect were noted, consistent with ischemic optic neuropathy. Conclusion: Retinal migraine can complicate with permanent monocular visual loss, suggesting potential migrainous infarction of the retina or optic nerve. A thorough cerebrovascular evaluation must be completed, which was unrevealing in our cases. Acute and preventive migraine therapy may be considered in retinal migraine patients, to mitigate rare but potentially permanent visual loss.

Original languageEnglish (US)
Pages (from-to)553-556
Number of pages4
Issue number6
StatePublished - May 2022


  • Retinal migraine
  • infarction
  • migrainous infarction
  • paracentral acute middle maculopathy
  • vision loss
  • visual aura

ASJC Scopus subject areas

  • Clinical Neurology


Dive into the research topics of 'Migrainous infarction of the eye: Two cases of monocular ischemic complications associated with retinal migraine'. Together they form a unique fingerprint.

Cite this