Migraine genetics - A review: Part i

Stephen Silberstein, David Dodick

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Significant progress in molecular genetics has advanced our understanding of the genetic basis of migraine. The fundamentals of molecular genetics, and the recent advances in the field, are important for clinicians to understand, as they provide a foundation for critical appraisal of the literature, unprecedented insights into the pathogenesis of the disorder, and reveal promising treatment targets for future drug development. This paper provides a primer of molecular genetics and will be followed by a companion paper on the genetic advances in migraine, the methodology of genome wide association studies, and the potential clinical implications.

Original languageEnglish (US)
Pages (from-to)1207-1217
Number of pages11
JournalHeadache
Volume53
Issue number8
DOIs
StatePublished - Sep 1 2013

Keywords

  • chromosome
  • codon
  • deoxyribonucleic acid
  • gene
  • ribonucleic acid

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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