Mid-infrared laser ablation of the cornea: A comparative study

Q. Ren, V. Venugopalan, K. Schomacker, T. F. Deutsch, Thomas J Flotte, C. A. Puliafito, R. Birngruber

Research output: Contribution to journalArticlepeer-review

61 Scopus citations


The ablation thresholds and patterns of collateral damage in cornea produced by Er:YAG (2.94 μm) and Er:YSGG (2.79 μm) lasers were measured. Two different pulse durations, 200 μs (normal spiking mode) and 100 ns (Q- switched mode), were used at both wavelengths. In the normal spiking mode, damage zones of 16 ± 2 μm and 39 ± 7 μm and ablation thresholds of 250 ± 20 mJ/cm 2 and 420 ± 35 mJ/cm 2 were measured at 2.94 μm and 2.79 μm, respectively. In the Q-switched mode, damage zones of 4 ± 2 μm and ablation thresholds of 150 ± 10 mJ/cm 2 were found irrespective of the laser used. The similarity between the results using the Er:YAG and Er:YSGG lasers in the Q-switched mode suggest that either laser can be used with equal effectiveness for corneal trephination.

Original languageEnglish (US)
Pages (from-to)274-281
Number of pages8
JournalLasers in Surgery and Medicine
Issue number3
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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