Microscopic colitides: A single center experience in Mexico

Alberto Rubio-Tapia, Julio Martínez-Salgado, Jorge García-Leiva, Braulio Martínez-Benítez, Misael Uribe

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Background/aim: Microscopic colitis is characterized by chronic diarrhea and specific microscopic changes in a macroscopically normal colonic mucosa. In this paper, we report the clinical and histological features of a group of Mexican patients with microscopic colitis. Materials and methods: Patients were identified from 10 years of data in the pathology database of our institution. A pathologist reassessed all biopsy material. We included only patients who met strict histopathological criteria. Clinical data were obtained from medical records. Results: Microscopic colitis was diagnosed in 26 cases. The female/male ratio was 1.8:1. The median age at diagnosis was 56.5 ± 15.7 (range, 26-85) years. The most frequent symptoms were diarrhea in all, weight loss in 22 (84%), and abdominal pain in 18 (69%) patients. Sixteen (61%) patients reported associated diseases; autoimmune thyroid disorders were the most common. Drug-induced microscopic colitis was suspected in 12 (46%) patients. More than 80% of the treated patients improved or had clinical remission. Conclusion: Microscopic colitis is an uncommon colonic disease at our institution, representing less than 1% of the final diagnoses in mucosal colonic biopsies. It is the largest case series of microscopic colitis in the Mexican population.

Original languageEnglish (US)
Pages (from-to)1031-1036
Number of pages6
JournalInternational Journal of Colorectal Disease
Volume22
Issue number9
DOIs
StatePublished - Sep 1 2007

Keywords

  • Collagenous colitis
  • Lymphocytic colitis
  • Microscopic colitis

ASJC Scopus subject areas

  • Gastroenterology

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    Rubio-Tapia, A., Martínez-Salgado, J., García-Leiva, J., Martínez-Benítez, B., & Uribe, M. (2007). Microscopic colitides: A single center experience in Mexico. International Journal of Colorectal Disease, 22(9), 1031-1036. https://doi.org/10.1007/s00384-006-0258-7