Micropatterned photodegradable hydrogels for the sorting of microbeads and cells

Christian Siltanen, Dong Sik Shin, Julie Sutcliffe, Alexander Revzin

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Sorted out: Soft-lithography micropatterning of a photodegradable poly(ethylene glycol) hydrogel was utilized to sort cell-bound microbeads. Biofunctionalized microbeads were patterned, screened for cell binding activity, and isolated from arrays by UV irradiation. The technique is a simple approach for sorting and downstream processing of cultured cells.

Original languageEnglish (US)
Pages (from-to)9224-9228
Number of pages5
JournalAngewandte Chemie - International Edition
Volume52
Issue number35
DOIs
StatePublished - Aug 26 2013

Keywords

  • cell sorting
  • hydrogels
  • microarray
  • micropatterning
  • soft lithography

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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