Microcytosis in agnogenic myeloid metaplasia: Prevalence and clinical correlates

Ayalew Tefferi, David Dingli, Chin Yang Li, Ruben A. Mesa

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Microcytosis is a characteristic laboratory feature for both iron deficiency anemia and thalassemia. It is also infrequently seen in "anemia of chronic disease" that accompanies a spectrum of chronic conditions including rheumatoid arthritis, polymyalgia rheumatica, diabetes mellitus, connective tissue disease, and protracted infection. In addition, there is a well established but pathogenetically obscure association of microcytosis with Hodgkin's lymphoma, Castleman's disease, and renal cell carcinoma. In the current study, we show that microcytosis is a frequent laboratory feature in agnogenic myeloid metaplasia and investigate its clinical relevance in the particular setting.

Original languageEnglish (US)
Pages (from-to)677-680
Number of pages4
JournalLeukemia Research
Volume30
Issue number6
DOIs
StatePublished - Jun 1 2006

Keywords

  • Incidence
  • Microcytosis
  • Myelofibrosis
  • Prognosis
  • Survival

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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