Micro gamma camera optics with high sensitivity and resolution

C. A. MacDonald, Noor Mail, W. M. Gibson, S. M. Jorgensen, E. L. Ritman

Research output: Contribution to journalConference article

3 Scopus citations

Abstract

Polycapillary x-ray optics are bundles of micron size hollow tubes, inside of which x rays are propagated by total reflection much like visible light in solid fiber optics. The small critical angle for total reflection from the glass walls of the tubes, 0.06° at 27 keV, results in very high angular selectivity. The field of view of each capillary tube is limited by this angular acceptance to less than 50 microns at a source-to-optic distance of 2 cm. Each adjacent tube works in parallel so that a large area can be covered at this resolution with much higher count rate than for a single collimator. Measurements have been performed using 125I brachytherapy seeds in Lucite phantoms using the optics and imaging detectors. Measured resolutions were detector-limited at better than 0.1 mm. Calculations for expected sensitivity and signal-to-background ratios were developed from geometrical models and show good agreement with measurements. Results indicate that the optics provide superior signal count rates to conventional collimators for geometries such as small animal imaging in which sub millimeter resolution with inch-wide or larger fields of view are desirable.

Original languageEnglish (US)
Article number01
Pages (from-to)1-6
Number of pages6
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume5745
Issue numberI
DOIs
StatePublished - Aug 25 2005
EventMedical Imaging 2005 - Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 13 2005Feb 15 2005

Keywords

  • Gammacamera
  • Nuclear medicine
  • Polycapillary x-ray optics
  • Radioscintigraphy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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    MacDonald, C. A., Mail, N., Gibson, W. M., Jorgensen, S. M., & Ritman, E. L. (2005). Micro gamma camera optics with high sensitivity and resolution. Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 5745(I), 1-6. [01]. https://doi.org/10.1117/12.597193