METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma

Xiangyu Zeng, Fei Zhao, Gaofeng Cui, Yong Zhang, Rajashree A. Deshpande, Yuping Chen, Min Deng, Jake A. Kloeber, Yu Shi, Qin Zhou, Chao Zhang, Jing Hou, Wootae Kim, Xinyi Tu, Yuanliang Yan, Zhijie Xu, Lifeng Chen, Huanyao Gao, Guijie Guo, Jiaqi LiuQian Zhu, Yueyu Cao, Jinzhou Huang, Zheming Wu, Shouhai Zhu, Ping Yin, Kuntian Luo, Georges Mer, Tanya T. Paull, Jian Yuan, Kaixiong Tao, Zhenkun Lou

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Medicine & Life Sciences