Methyllysine recognition by the royal family modules: Chromo, tudor, MBT, chromo barrel, and PWWP domains

Chao Xu, Gaofeng Cui, Maria Victoria Botuyan, Georges Mer

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Protein domains of the Royal Family were the first methyllysine binding domains to be discovered. Here, we review what was learned from the structural studies of Royal Family members including chromo, Tudor, MBT, chromo barrel, and PWWP domains. Our main focus is on methyllysine reader domains for which three-dimensional structures are available in the ligand-bound state.

Original languageEnglish (US)
Title of host publicationHistone Recognition
PublisherSpringer International Publishing
Pages49-82
Number of pages34
ISBN (Electronic)9783319181028
ISBN (Print)9783319181011
DOIs
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology

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