Methylation pharmacogenetics: Thiopurine methyltransferase as a model system

Medicine & Life Sciences

• thiopurine methyltransferase 93%
• Pharmacogenetics 68%
• Methylation 54%
• Methyltransferases 28%
• Enzymes 23%
• Pharmaceutical Preparations 21%
• Biotransformation 20%
• Erythrocytes 20%
• Genetic Polymorphisms 18%
• thiol S-methyltransferase 17%
• Histamine N-Methyltransferase 14%
• Catechol O-Methyltransferase 11%
• Mercaptopurine 11%
• Pharmacogenomic Testing 11%
• Inbred Strains Mice 10%
• Xenobiotics 9%
• Toxicology 8%
• Therapeutic Uses 7%
• Animal Models 6%
• Pharmacology 5%

Chemical Compounds

• Thiopurine 100%
• Genetic Polymorphism 21%
• Drug 14%
• Red 13%
• Enzyme Activity 11%
• Xenobiotic Agent 7%
• Histamine 7%
• Catechol 6%
• Thiol 5%
• Pharmacological Metabolism 5%
• Strain 4%