TY - JOUR
T1 - Methodological standards and patient-centeredness in comparative effectiveness research
T2 - The PCORI perspective
AU - Basch, Ethan
AU - Aronson, Naomi
AU - Berg, Alfred
AU - Flum, David
AU - Gabriel, Sherine
AU - Goodman, Steven N.
AU - Helfand, Mark
AU - Ioannidis, John P.A.
AU - Lauer, Michael
AU - Meltzer, David
AU - Mittman, Brian
AU - Newhouse, Robin
AU - Normand, Sharon Lise
AU - Schneeweiss, Sebastian
AU - Slutsky, Jean
AU - Tinetti, Mary
AU - Yancy, Clyde
PY - 2012/4/18
Y1 - 2012/4/18
N2 - Rigorous methodological standards help to ensure that medical research produces information that is valid and generalizable, and are essential in patientcentered outcomes research (PCOR). Patient-centeredness refers to the extent to which the preferences, decision-making needs, and characteristics of patients are addressed, and is the key characteristic differentiating PCOR from comparative effectiveness research. The Patient Protection and Affordable Care Act signed into law in 2010 created the Patient-Centered Outcomes Research Institute (PCORI), which includes an independent, federally appointed Methodology Committee. The Methodology Committee is charged to develop methodological standards for PCOR. The 4 general areas identified by the committee in which standards will be developed are (1) prioritizing research questions, (2) using appropriate study designs and analyses, (3) incorporating patient perspectives throughout the research continuum, and (4) fostering efficient dissemination and implementation of results. A Congressionally mandated PCORI methodology report (to be issued in its first iteration in May 2012) will begin to provide standards in each of these areas, and will inform future PCORI funding announcements and review criteria. The work of the Methodology Committee is intended to enable generation of information that is relevant and trustworthy for patients, and to enable decisions that improve patient-centered outcomes.
AB - Rigorous methodological standards help to ensure that medical research produces information that is valid and generalizable, and are essential in patientcentered outcomes research (PCOR). Patient-centeredness refers to the extent to which the preferences, decision-making needs, and characteristics of patients are addressed, and is the key characteristic differentiating PCOR from comparative effectiveness research. The Patient Protection and Affordable Care Act signed into law in 2010 created the Patient-Centered Outcomes Research Institute (PCORI), which includes an independent, federally appointed Methodology Committee. The Methodology Committee is charged to develop methodological standards for PCOR. The 4 general areas identified by the committee in which standards will be developed are (1) prioritizing research questions, (2) using appropriate study designs and analyses, (3) incorporating patient perspectives throughout the research continuum, and (4) fostering efficient dissemination and implementation of results. A Congressionally mandated PCORI methodology report (to be issued in its first iteration in May 2012) will begin to provide standards in each of these areas, and will inform future PCORI funding announcements and review criteria. The work of the Methodology Committee is intended to enable generation of information that is relevant and trustworthy for patients, and to enable decisions that improve patient-centered outcomes.
UR - http://www.scopus.com/inward/record.url?scp=84859863807&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859863807&partnerID=8YFLogxK
U2 - 10.1001/jama.2012.466
DO - 10.1001/jama.2012.466
M3 - Review article
C2 - 22511692
AN - SCOPUS:84859863807
SN - 0098-7484
VL - 307
SP - 1636
EP - 1640
JO - JAMA
JF - JAMA
IS - 15
ER -