Methicillin-Resistant Staphylococcus aureus Infection and Treatment Options

Sarah J. Chalmers, Mark Wylam

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of infection worldwide, including a wide array of both hospital- and community-acquired infections-most commonly bacteremia, upper and lower respiratory tract infection, skin and soft-tissue infection, osteomyelitis, and septic arthritis. This chapter describes the epidemiology of MRSA infection, its ability to confer antibiotic resistance and produce a wide array of virulence factors, and its pivotal role in human infection, especially cystic fibrosis. It also provides an introduction to the strategies for treatment of both chronic and acute MRSA infections.

Original languageEnglish (US)
Pages (from-to)229-251
Number of pages23
JournalMethods in molecular biology (Clifton, N.J.)
Volume2069
DOIs
StatePublished - Jan 1 2020

Keywords

  • Bacteremia
  • Community acquired
  • Hospital acquired
  • Lung infection
  • Methicillin-resistant Staphylococcus aureus

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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