TY - JOUR
T1 - Methicillin-Resistant Staphylococcus aureus Infection and Treatment Options
AU - Chalmers, Sarah J.
AU - Wylam, Mark
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of infection worldwide, including a wide array of both hospital- and community-acquired infections-most commonly bacteremia, upper and lower respiratory tract infection, skin and soft-tissue infection, osteomyelitis, and septic arthritis. This chapter describes the epidemiology of MRSA infection, its ability to confer antibiotic resistance and produce a wide array of virulence factors, and its pivotal role in human infection, especially cystic fibrosis. It also provides an introduction to the strategies for treatment of both chronic and acute MRSA infections.
AB - Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of infection worldwide, including a wide array of both hospital- and community-acquired infections-most commonly bacteremia, upper and lower respiratory tract infection, skin and soft-tissue infection, osteomyelitis, and septic arthritis. This chapter describes the epidemiology of MRSA infection, its ability to confer antibiotic resistance and produce a wide array of virulence factors, and its pivotal role in human infection, especially cystic fibrosis. It also provides an introduction to the strategies for treatment of both chronic and acute MRSA infections.
KW - Bacteremia
KW - Community acquired
KW - Hospital acquired
KW - Lung infection
KW - Methicillin-resistant Staphylococcus aureus
UR - http://www.scopus.com/inward/record.url?scp=85072204202&partnerID=8YFLogxK
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U2 - 10.1007/978-1-4939-9849-4_16
DO - 10.1007/978-1-4939-9849-4_16
M3 - Article
C2 - 31523777
AN - SCOPUS:85072204202
SN - 1064-3745
VL - 2069
SP - 229
EP - 251
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
ER -