Metastases to the pituitary gland

Hassan M. Heshmati, Bernd W. Scheithauer, William Francis Young

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Pituitary metastasis is a rare cause of an intrasellar mass. The authors report a series of 52 patients with intrasellar metastases diagnosed between 1950 and 1996. The patient group included 29 women and 23 men with a mean age of 60 years. Breast and lung carcinomas were the most frequent primary tumors (37% and 23%, respectively). The primary tumor was unknown in 12% of patients. In the patients with a known primary tumor, it was diagnosed after the pituitary metastasis was discovered in 20%. The mode of discovery of pituitary metastases was symptom-based (visual impairment, diabetes insipidus, hypopituitarism) in 75% of patients. Of the patients in whom prolactin was measured, 63% had hyperprolactinemia. Computed tomography and magnetic resonance imaging of the brain, available for 52% and 19% of patients, respectively, showed a pituitary mass in each case. Pituitary surgery and radiotherapy were performed in 42% and 63% of patients, respectively. Mean survival was 17 months (range, 0-240 months). Overall mortality at 1 year was 67%.

Original languageEnglish (US)
Pages (from-to)45-49
Number of pages5
JournalEndocrinologist
Volume12
Issue number1
StatePublished - 2002

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Pituitary Gland
Neoplasm Metastasis
Unknown Primary Neoplasms
Hypopituitarism
Diabetes Insipidus
Hyperprolactinemia
Vision Disorders
Prolactin
Neoplasms
Radiotherapy
Tomography
Magnetic Resonance Imaging
Breast Neoplasms
Lung
Survival
Mortality
Brain

ASJC Scopus subject areas

  • Endocrinology

Cite this

Heshmati, H. M., Scheithauer, B. W., & Young, W. F. (2002). Metastases to the pituitary gland. Endocrinologist, 12(1), 45-49.

Metastases to the pituitary gland. / Heshmati, Hassan M.; Scheithauer, Bernd W.; Young, William Francis.

In: Endocrinologist, Vol. 12, No. 1, 2002, p. 45-49.

Research output: Contribution to journalArticle

Heshmati, HM, Scheithauer, BW & Young, WF 2002, 'Metastases to the pituitary gland', Endocrinologist, vol. 12, no. 1, pp. 45-49.
Heshmati HM, Scheithauer BW, Young WF. Metastases to the pituitary gland. Endocrinologist. 2002;12(1):45-49.
Heshmati, Hassan M. ; Scheithauer, Bernd W. ; Young, William Francis. / Metastases to the pituitary gland. In: Endocrinologist. 2002 ; Vol. 12, No. 1. pp. 45-49.
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