Meta-analysis of meta-analyses of anterior cruciate ligament injury reduction training programs

Kate E. Webster, Timothy Hewett

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Several meta-analyses have been published on the effectiveness of anterior cruciate ligament (ACL) injury prevention training programs to reduce ACL injury risk, with various degrees of risk reduction reported. The purpose of this research was to perform a systematic review and meta-analysis of overlapping meta-analyses evaluating the effectiveness of ACL injury prevention training programs so as to summarize the amount of reduction in risk for all ACL and non-contact ACL injuries into a single source, and determine if there were sex differences in the relative efficacy of ACL injury prevention training programs. Five databases (Medline, PubMed, Embase, CINAHL, and Cochrane) were searched to identify meta-analyses that evaluated the effectiveness of ACL injury prevention training programs on ACL injury risk. ACL injury data were extracted and the results from each meta-analysis were combined using a summary meta-analysis based on odds ratios (OR). Eight meta-analyses met eligibility criteria. Six of the eight only included data for female athletes. Summary meta-analysis showed an overall 50% reduction (OR = 0.5 [0.41–0.59]; I2 = 15%) in the risk of all ACL injuries in all athletes and a 67% reduction (OR = 0.33 [0.27–0.41]; I2 = 15%) for non-contact ACL injuries in females. This paper combines all previous meta-analyses into a single source and shows conclusive evidence that ACL injury prevention programs reduce the risk of all ACL injuries by half in all athletes and non-contact ACL injuries by two-thirds in female athletes. There is insufficient data to make conclusions as to the effectiveness of ACL injury prevention programs in male athletes.

Original languageEnglish (US)
Pages (from-to)2696-2708
Number of pages13
JournalJournal of Orthopaedic Research
Volume36
Issue number10
DOIs
StatePublished - Oct 1 2018

Fingerprint

Meta-Analysis
Education
Athletes
Odds Ratio
Risk Reduction Behavior
Anterior Cruciate Ligament Injuries
Anterior Cruciate Ligament
PubMed
Sex Characteristics
Databases

Keywords

  • anterior cruciate ligament
  • injury prevention
  • neuromuscular training
  • sports injury

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Meta-analysis of meta-analyses of anterior cruciate ligament injury reduction training programs. / Webster, Kate E.; Hewett, Timothy.

In: Journal of Orthopaedic Research, Vol. 36, No. 10, 01.10.2018, p. 2696-2708.

Research output: Contribution to journalArticle

@article{ccc4cd67594c4c498f68f06cb157a11f,
title = "Meta-analysis of meta-analyses of anterior cruciate ligament injury reduction training programs",
abstract = "Several meta-analyses have been published on the effectiveness of anterior cruciate ligament (ACL) injury prevention training programs to reduce ACL injury risk, with various degrees of risk reduction reported. The purpose of this research was to perform a systematic review and meta-analysis of overlapping meta-analyses evaluating the effectiveness of ACL injury prevention training programs so as to summarize the amount of reduction in risk for all ACL and non-contact ACL injuries into a single source, and determine if there were sex differences in the relative efficacy of ACL injury prevention training programs. Five databases (Medline, PubMed, Embase, CINAHL, and Cochrane) were searched to identify meta-analyses that evaluated the effectiveness of ACL injury prevention training programs on ACL injury risk. ACL injury data were extracted and the results from each meta-analysis were combined using a summary meta-analysis based on odds ratios (OR). Eight meta-analyses met eligibility criteria. Six of the eight only included data for female athletes. Summary meta-analysis showed an overall 50{\%} reduction (OR = 0.5 [0.41–0.59]; I2 = 15{\%}) in the risk of all ACL injuries in all athletes and a 67{\%} reduction (OR = 0.33 [0.27–0.41]; I2 = 15{\%}) for non-contact ACL injuries in females. This paper combines all previous meta-analyses into a single source and shows conclusive evidence that ACL injury prevention programs reduce the risk of all ACL injuries by half in all athletes and non-contact ACL injuries by two-thirds in female athletes. There is insufficient data to make conclusions as to the effectiveness of ACL injury prevention programs in male athletes.",
keywords = "anterior cruciate ligament, injury prevention, neuromuscular training, sports injury",
author = "Webster, {Kate E.} and Timothy Hewett",
year = "2018",
month = "10",
day = "1",
doi = "10.1002/jor.24043",
language = "English (US)",
volume = "36",
pages = "2696--2708",
journal = "Journal of Orthopaedic Research",
issn = "0736-0266",
publisher = "John Wiley and Sons Inc.",
number = "10",

}

TY - JOUR

T1 - Meta-analysis of meta-analyses of anterior cruciate ligament injury reduction training programs

AU - Webster, Kate E.

AU - Hewett, Timothy

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Several meta-analyses have been published on the effectiveness of anterior cruciate ligament (ACL) injury prevention training programs to reduce ACL injury risk, with various degrees of risk reduction reported. The purpose of this research was to perform a systematic review and meta-analysis of overlapping meta-analyses evaluating the effectiveness of ACL injury prevention training programs so as to summarize the amount of reduction in risk for all ACL and non-contact ACL injuries into a single source, and determine if there were sex differences in the relative efficacy of ACL injury prevention training programs. Five databases (Medline, PubMed, Embase, CINAHL, and Cochrane) were searched to identify meta-analyses that evaluated the effectiveness of ACL injury prevention training programs on ACL injury risk. ACL injury data were extracted and the results from each meta-analysis were combined using a summary meta-analysis based on odds ratios (OR). Eight meta-analyses met eligibility criteria. Six of the eight only included data for female athletes. Summary meta-analysis showed an overall 50% reduction (OR = 0.5 [0.41–0.59]; I2 = 15%) in the risk of all ACL injuries in all athletes and a 67% reduction (OR = 0.33 [0.27–0.41]; I2 = 15%) for non-contact ACL injuries in females. This paper combines all previous meta-analyses into a single source and shows conclusive evidence that ACL injury prevention programs reduce the risk of all ACL injuries by half in all athletes and non-contact ACL injuries by two-thirds in female athletes. There is insufficient data to make conclusions as to the effectiveness of ACL injury prevention programs in male athletes.

AB - Several meta-analyses have been published on the effectiveness of anterior cruciate ligament (ACL) injury prevention training programs to reduce ACL injury risk, with various degrees of risk reduction reported. The purpose of this research was to perform a systematic review and meta-analysis of overlapping meta-analyses evaluating the effectiveness of ACL injury prevention training programs so as to summarize the amount of reduction in risk for all ACL and non-contact ACL injuries into a single source, and determine if there were sex differences in the relative efficacy of ACL injury prevention training programs. Five databases (Medline, PubMed, Embase, CINAHL, and Cochrane) were searched to identify meta-analyses that evaluated the effectiveness of ACL injury prevention training programs on ACL injury risk. ACL injury data were extracted and the results from each meta-analysis were combined using a summary meta-analysis based on odds ratios (OR). Eight meta-analyses met eligibility criteria. Six of the eight only included data for female athletes. Summary meta-analysis showed an overall 50% reduction (OR = 0.5 [0.41–0.59]; I2 = 15%) in the risk of all ACL injuries in all athletes and a 67% reduction (OR = 0.33 [0.27–0.41]; I2 = 15%) for non-contact ACL injuries in females. This paper combines all previous meta-analyses into a single source and shows conclusive evidence that ACL injury prevention programs reduce the risk of all ACL injuries by half in all athletes and non-contact ACL injuries by two-thirds in female athletes. There is insufficient data to make conclusions as to the effectiveness of ACL injury prevention programs in male athletes.

KW - anterior cruciate ligament

KW - injury prevention

KW - neuromuscular training

KW - sports injury

UR - http://www.scopus.com/inward/record.url?scp=85053876192&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85053876192&partnerID=8YFLogxK

U2 - 10.1002/jor.24043

DO - 10.1002/jor.24043

M3 - Article

C2 - 29737024

AN - SCOPUS:85053876192

VL - 36

SP - 2696

EP - 2708

JO - Journal of Orthopaedic Research

JF - Journal of Orthopaedic Research

SN - 0736-0266

IS - 10

ER -