Mesenchymal stem cells as alternative therapy for brain disorders and their interaction with the immune system

Qian Li, Kaisorn L. Chaichana, Julio J. Rodarte, Alfredo Quinones-Hinojosa, Hugo Guerrero Cazares

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Mesenchymal stem cells (MSCs) are cells that have the ability to maintain, self-renew, and give rise to different stromal cell types. These cells can be obtained from a variety of sources that includes bone marrow and adipose tissue. MSCs have an intrinsic tropism towards inflammation and tumor tissues, which makes them an attractive candidate for cellularbased therapies. This chapter summarizes the properties of different sources of MSCs, their potential therapeutic use for brain tumor and other brain disorders, and their interaction with immune system cells. Ultimately, MSCs represent a promising new cellular therapy paradigm where these cells can be used as delivery vehicles for therapeutic molecules or serve as a source of replacement cells in degenerative diseases.

Original languageEnglish (US)
Title of host publicationNeuro-Immune Interactions in the Adult Central Nervous System
PublisherNova Science Publishers, Inc.
Pages87-108
Number of pages22
ISBN (Electronic)9781631171291
ISBN (Print)9781629486468
StatePublished - Jan 1 2014
Externally publishedYes

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Brain Diseases
Complementary Therapies
Mesenchymal Stromal Cells
Immune System
Tropism
Therapeutic Uses
Stromal Cells
Cell- and Tissue-Based Therapy
Brain Neoplasms
Adipose Tissue
Bone Marrow
Inflammation
Bone and Bones
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Li, Q., Chaichana, K. L., Rodarte, J. J., Quinones-Hinojosa, A., & Guerrero Cazares, H. (2014). Mesenchymal stem cells as alternative therapy for brain disorders and their interaction with the immune system. In Neuro-Immune Interactions in the Adult Central Nervous System (pp. 87-108). Nova Science Publishers, Inc..

Mesenchymal stem cells as alternative therapy for brain disorders and their interaction with the immune system. / Li, Qian; Chaichana, Kaisorn L.; Rodarte, Julio J.; Quinones-Hinojosa, Alfredo; Guerrero Cazares, Hugo.

Neuro-Immune Interactions in the Adult Central Nervous System. Nova Science Publishers, Inc., 2014. p. 87-108.

Research output: Chapter in Book/Report/Conference proceedingChapter

Li, Q, Chaichana, KL, Rodarte, JJ, Quinones-Hinojosa, A & Guerrero Cazares, H 2014, Mesenchymal stem cells as alternative therapy for brain disorders and their interaction with the immune system. in Neuro-Immune Interactions in the Adult Central Nervous System. Nova Science Publishers, Inc., pp. 87-108.
Li Q, Chaichana KL, Rodarte JJ, Quinones-Hinojosa A, Guerrero Cazares H. Mesenchymal stem cells as alternative therapy for brain disorders and their interaction with the immune system. In Neuro-Immune Interactions in the Adult Central Nervous System. Nova Science Publishers, Inc. 2014. p. 87-108
Li, Qian ; Chaichana, Kaisorn L. ; Rodarte, Julio J. ; Quinones-Hinojosa, Alfredo ; Guerrero Cazares, Hugo. / Mesenchymal stem cells as alternative therapy for brain disorders and their interaction with the immune system. Neuro-Immune Interactions in the Adult Central Nervous System. Nova Science Publishers, Inc., 2014. pp. 87-108
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