Memory function in normal aging

Ronald Carl Petersen, G. Smith, E. Kokmen, R. J. Ivnik, Eric George Tangalos

Research output: Contribution to journalArticle

209 Citations (Scopus)

Abstract

We evaluated memory function in a group of 161 community-dwelling, cognitively normal individuals aged 62 to 100 years recruited as part of the Mayo Clinic Alzheimer's Disease Patient Registry. We used the Free and Cued Selective Reminding Test and the Rey Auditory Verbal Learning Test to evaluate two aspects of memory function thought to be sensitive to the effects of aging: learning (acquisition) and delayed recall (forgetting). The results were quite consistent and demonstrated that learning or acquisition performance declines uniformly with increasing age but is not related to education. Delayed recall or forgetting, however, remained relatively stable across age when adjusted for the amount of material initially learned. These findings are relevant for assessing normal memory function relative to the early impairments found in dementia and form a baseline against which memory performance can be assessed by the clinician. In particular, suspicion regarding a disorder of brain function affecting memory processes should be raised if learning performance declines more rapidly than expected or if delayed recall is impaired to any significant extent.

Original languageEnglish (US)
Pages (from-to)396-401
Number of pages6
JournalNeurology
Volume42
Issue number2
StatePublished - Feb 1992

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Learning
Independent Living
Verbal Learning
Brain Diseases
Dementia
Registries
Alzheimer Disease
Education

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Petersen, R. C., Smith, G., Kokmen, E., Ivnik, R. J., & Tangalos, E. G. (1992). Memory function in normal aging. Neurology, 42(2), 396-401.

Memory function in normal aging. / Petersen, Ronald Carl; Smith, G.; Kokmen, E.; Ivnik, R. J.; Tangalos, Eric George.

In: Neurology, Vol. 42, No. 2, 02.1992, p. 396-401.

Research output: Contribution to journalArticle

Petersen, RC, Smith, G, Kokmen, E, Ivnik, RJ & Tangalos, EG 1992, 'Memory function in normal aging', Neurology, vol. 42, no. 2, pp. 396-401.
Petersen RC, Smith G, Kokmen E, Ivnik RJ, Tangalos EG. Memory function in normal aging. Neurology. 1992 Feb;42(2):396-401.
Petersen, Ronald Carl ; Smith, G. ; Kokmen, E. ; Ivnik, R. J. ; Tangalos, Eric George. / Memory function in normal aging. In: Neurology. 1992 ; Vol. 42, No. 2. pp. 396-401.
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