Abstract
Hemicrania continua is one of the indomethacin-responsive headache syndromes. There are very few effective alternative therapies for hemicrania continua, thus patients may require daily indomethacin for years. The risks of long-term indomethacin include gastrointestinal and renal dysfunction. Melatonin is a pineal hormone with a chemical structure very similar to indomethacin. Recently, melatonin was shown to be effective for primary stabbing headache, another indomethacin-responsive syndrome. Three cases of melatonin responsive hemicrania continua are now reported.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1203-1204 |
| Number of pages | 2 |
| Journal | Headache |
| Volume | 46 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2006 |
Keywords
- Hemicrania continua
- Indomethacin
- Melatonin
ASJC Scopus subject areas
- Neurology
- Clinical Neurology