Melatonin in the preventive treatment of chronic cluster headache

M. F P Peres, Todd Rozen

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Cluster headache is a stereotypic headache disorder marked by short-lasting bouts of severe unilateral head pain and associated autonomic symptoms. Almost pathognomonic of this condition are nocturnal attacks that usually occur during the first random eye movement sleep phase of the evening. Melatonin levels have been found to be decreased in cluster headache patients. A lack of melatonin secretion may predispose the cluster sufferer to nocturnal and, possibly, daytime attacks. Leone et al. demonstrated that melatonin could rapidly alleviate cluster attacks, but only in episodic cluster patients. We report two chronic cluster headache patients who had both daytime and nocturnal attacks that were alleviated with melatonin.

Original languageEnglish (US)
Pages (from-to)993-995
Number of pages3
JournalCephalalgia
Volume21
Issue number10
DOIs
StatePublished - Dec 1 2001
Externally publishedYes

Fingerprint

Cluster Headache
Melatonin
Headache Disorders
Therapeutics
Eye Movements
Headache
Sleep

Keywords

  • Chronic cluster headache
  • Melatonin
  • Preventive treatment

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Melatonin in the preventive treatment of chronic cluster headache. / Peres, M. F P; Rozen, Todd.

In: Cephalalgia, Vol. 21, No. 10, 01.12.2001, p. 993-995.

Research output: Contribution to journalArticle

Peres, M. F P ; Rozen, Todd. / Melatonin in the preventive treatment of chronic cluster headache. In: Cephalalgia. 2001 ; Vol. 21, No. 10. pp. 993-995.
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