Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients

Farrah Mateen, Aminah Jatoi

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Anorexia, or loss of appetite, is a troubling symptom for many patients with advanced cancer. The early observation that breast cancer patients, who were prescribed megestrol acetate as a cancer treatment, went on to increase their appetite and gain weight has given rise to a large number of clinical trials that have tested this progestational drug as a palliative agent for the cancer anorexia/weight loss syndrome. This review focuses on these trials, summarizing their findings and providing a practical approach for prescribing megestrol acetate to advanced cancer patients who suffer from the cancer anorexia/weight loss syndrome.

Original languageEnglish (US)
Pages (from-to)711-715
Number of pages5
JournalClinical Nutrition
Volume25
Issue number5
DOIs
StatePublished - Oct 1 2006

Keywords

  • Anorexia
  • Cancer
  • Megestrol acetate
  • Palliation

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Critical Care and Intensive Care Medicine

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