Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients

Farrah Mateen, Aminah Jatoi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Anorexia, or loss of appetite, is a troubling symptom for many patients with advanced cancer. The early observation that breast cancer patients, who were prescribed megestrol acetate as a cancer treatment, went on to increase their appetite and gain weight has given rise to a large number of clinical trials that have tested this progestational drug as a palliative agent for the cancer anorexia/weight loss syndrome. This review focuses on these trials, summarizing their findings and providing a practical approach for prescribing megestrol acetate to advanced cancer patients who suffer from the cancer anorexia/weight loss syndrome.

Original languageEnglish (US)
Pages (from-to)711-715
Number of pages5
JournalClinical Nutrition
Volume25
Issue number5
DOIs
StatePublished - Oct 2006

Fingerprint

Megestrol Acetate
Anorexia
Appetite
Neoplasms
Weight Loss
Weight Gain
Clinical Trials
Breast Neoplasms
Pharmaceutical Preparations

Keywords

  • Anorexia
  • Cancer
  • Megestrol acetate
  • Palliation

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Endocrinology, Diabetes and Metabolism
  • Gastroenterology
  • Health Professions(all)
  • Medicine (miscellaneous)

Cite this

Megestrol acetate for the palliation of anorexia in advanced, incurable cancer patients. / Mateen, Farrah; Jatoi, Aminah.

In: Clinical Nutrition, Vol. 25, No. 5, 10.2006, p. 711-715.

Research output: Contribution to journalArticle

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